Effect of Lupus Nephritis on Cardiac Remodeling and Left Ventricular Relative Wall Thickness

SEFA TATAR, AHMET TAHA ŞAHİN, Yunus Emre Yavuz, Hüseyin Özer, Bryan Nicolalde, Nuraiym Moloshova, MUSTAFA ÇAĞRI ERGÜN

  • Year : 2025
  • Vol : 41
  • Issue : 2
  •  Page : 89-93
ABSTRACT
 Aim: Systemic Lupus Erythematosus (SLE) is an autoimmune disease associated with an increased risk of cardiovascular problems. Our objective is to investigate the effect of renal involvement in SLE on left ventricular relative wall thickness (RWT).
Materials and Methods: A single-center observational study was conducted to compare the echocardiographic characteristics of patients with SLE who had lupus nephritis and those without. A total of 125 patients were included in the study.
Results: The mean age was 31 years in patients with lupus nephritis and 40 years in those without. In patients with lupus nephritis, the interventricular septum thickness was found to be thinner. The Mitral A wave was lower in patients with lupus nephritis (62.5±17 vs. 74.9±20.5, p<0.05). Left ventricular relative wall thickness (RWT) was calculated to be lower in patients with lupus nephritis (0.38±0.06 vs. 0.43±0.07, p<0.05).
Conclusion: The development of lupus nephritis has a significant impact on myocardial function, and left ventricular RWT is an important parameter associated with adverse cardiovascular outcomes.
Keywords: Systemic Lupus Erythematosus, lupus nephritis, left ventricle, relative wall thickness, diastolic dysfunction
Cite this Article As : Tatar S, Sahin AT, Yavuz YE, Ozer H, Nicolalde B, Moloshova N, Ergun MC. Effect of Lupus Nephritis on Cardiac Remodeling and Left Ventricular Relative Wall Thickness. Selcuk Med J 2025;41(2): 89-93

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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Effect of Lupus Nephritis on Cardiac Remodeling and Left Ventricular Relative Wall Thickness
, Vol. 41 (2)
Received : 07.07.2024, Accepted : 10.11.2024, Published Online : 27.06.2025
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;