Full facial Resurfacing followed by Enucleation in a Patient with Xeroderma Pigmentosum: A Case Report

ABSTRACT
Xeroderma Pigmentosum is a rare autosomal recessive genetic disorder that marked by defective DNA repair mechanisms. We present a unique case of Xeroderma Pigmentosum in a 26-year-old Middle Eastern female who exhibited recurrent skin tumors, leading to substantial cosmetic and health-related challenges. The decision to perform a facial resurfacing operation with partial thickness skin graft was made to address the multiple lesions on the face and to improve the patient's quality of life. The procedure was successful in preventing the development of new tumors on the resurfaced skin during the follow-up period. However, one year following the resurfacing operation the subsequent development of a mass protruding from the patient's left globe highlights the aggressive nature of tumors in patients with Xeroderma Pigmentosum. Enucleation was recommended to prevent further complications. To our knowledge, this is a rare case in which both facial resurfacing and enucleation were performed concurrently in a single patient.
Keywords: Xeroderma Pigmentosum, Enucleation, resurfacing, Squamous Cell Carcinoma, Malignant Melanoma,