Proliferating celi nuclear antigen (PCNA) expression in cutaneous keratinous neoplasms

NEZAHAT YILDIRIM

  • Year : 2003
  • Vol : 19
  • No : 2
  •  Page : 65-69
Usually markers for proliferating cells need freshly frozen tissues for evaluation; therefore retrospective study is impossible. Proliferating celi nuclear antigen (PCNA) isapplicable to formalin-fixed, paraffin embedded tissues. İn this study, PCNA expression in cutaneous keratinous neoplasms were determined by immunohistochemical stain- ing using the 19A2 done. Sçuamous celi carcinoma (SCC) a unique expression of PCNA, which frequently involved the nuclei of ali keratinocytes vvithin the lesion was found. PCNA expression in verruca vulgaris (VV) and found a pattern similar to that in SCC. SCC and VV showed significantly increased numbers of PCNA positive cells when compared with other keratinocytic neoplasms.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Proliferating celi nuclear antigen (PCNA) expression in cutaneous keratinous neoplasms
, Vol. 19 (2)
Received : 25.11.2002, Accepted : 25.11.2002, Published Online : 01.10.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;