The Renal Cystic Development in Offsprings of Pregnant RaLs That Fed With Diphenylamine Derivates.

ALİ ACAR, RECAİ GÜRBÜZ, ŞÜKRÜ ÇELİK, HASAN HÜSEYİN TELLİ, Mehmet Özeroğlu, Özden Vural, Esat M. Arslan

  • Year : 1994
  • Vol : 10
  • No : 3
  •  Page : 297-303
The pre vtant rats were fed with diphenylamine derivatives (. tmilorid dihidrat + hid-roelorothiafid) clurin,,? the last week of gestation ins-pired by phanesetin and its major metabolic bre-akdown products are similar chemically diphenvlamine. The di (frrence., that reminded glomerulocystic kidney were -determined with histopathologie exa-mination in kidneys of offvpriti;,- However this dif-frrenees were not noted in olIcpi-inf;s or rats that led normally. We conclude that fetal kidney is susceptible to the interstitial intiantatory elkcts of phanacetin lie-rivairives and the resultmz tubular obstruction pro-duced the cystic changes.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
The Renal Cystic Development in Offsprings of Pregnant RaLs That Fed With Diphenylamine Derivates.
, Vol. 10 (3)
Received : 16.10.1994, Accepted : 16.10.1994, Published Online : 16.10.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;