Yıl: 1995, Cilt: 11, Sayı: 1
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Koagulaz - Negatıf Stafılokoklar Uzerıne Topıkal Antımıkrobıyal Ajanların Etkisi
Naci Kemal Kırca, Hüseyin Tol, Mahmut Baykan, Ali Sütçü, Fatma Keklikoğlu, Bülent Baysal, Hüseyin Endoğru
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Koagulaz - Negatıf Stafılokoklar Uzerıne Topıkal Antımıkrobıyal Ajanların Etkisi
Effect Of TopIcal AntImIcrobIal Agents On Co-Agulase-NegatIve StaphylococcI
Deri yazeyinde hulunan koagalaz-negatif sta-filokoklara topikal olarak uygulanan antimikrobiyal ajanlarin etkirzligi araorrildr. 5 antiseptik solusyon ye 5 antimikrobiyal pomat degerlendirildi. Antiseptik solusyonlar (% 10 Po-. vidone-iodine, % 2 iodine, % 2 Tentardiyot, % 70 etanol, % 0.5 Klorhekzidin) gazli hezle 15 saniye uy-gulandi. Antimikrobiyal pon-zadlar (mupirocin, neomycin-bacitracin • silver sulfadiazirz, povidone-iodine pomad. sodywn fusidat) gazli hezle 6 saw sareyle tathik edildi. Tedavi uygulamalarrndan sonra arnekler Povidone-iodine. Klorhekzidin ye tentiirdiyot dim Orneklerde (10110) yilzey bakterikrini eradike etti. % 2 iodine 10 ornegin 9'unda, % 70 etanol ise lo ornegin 7'sinde eradike edici hulundu. 5 antimikrobiyal pomadm 471 deri yazeyinin ste-rilizasyonunda etkin hulundu. % Silver sal-fadiazinVe 10 ornekten 2'cinde koagiilaz negatif sta-filokok arernesi goralda.
In the Human Skin The efficacy of antimicrobial agents applied to-pically to the skin surface in eradicating coagulase-negative staphylococci (ENS) residing in the skin surface. Five antiseptic solutions (10 % povidone iodine, 2 % iodine, 2 % tincture of iodine, 70 % ethanol, and 0.5 % Chlorhexidine) were applied for 15s with a gauze sponge. The antimicrobial ointments (po-vidone-iodine. silver sulfadiazine, mupirocin, so-dium fucidate, and a double-antibiotic ointment con-taining neomycine, and bacitracin) were applied and covered for 6 th with gauze. After treatment. the surface was sampled. All agents were effective in eradicating ENS from the surface. The antiseptic solutions povidone-iodine. chlor-hexidine and tincture of iodine eradicated surface bacteria in every trial (10 of 10 each), and 2 % io-dine and 70 % ethanol eradicated bacteria from the surface in 9 and 7 of 10 trials, respectively. Four of the five antimicrobial ointments were also effective in the sterilization of the skin sur-face: 1 % silver sulfadiazine was the exception.
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Akcıger Kıst Hıdatıgınde Cerrahı Yaklasım
Sami Ceran, Tahir Yüksek, Güven Sadi Sunam, Mehmet Gök, Hasan Solak, Kazım Gürol Akyol, Aydın Şanlı, Tunç Solak
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Akcıger Kıst Hıdatıgınde Cerrahı Yaklasım
SurgIcal InterventIon In The Lung HydatId Cyst
1987-1994 yillari arasinda S.O. Tip Fakiiltesi Grips Ka1p Damar Cerrahisi Klinigirte witirilarak tedavi edilen 191 pasta sunuldu. Vakalarin % 52.87si erkek, % 47.12'si kadindi. En cok gririilme 11-20 yak gruhundaydi. Kistin 99 (% 51.83)'ii sag akcikerde, 84 (% 43.97)'6 sol akcikerde ve 8 (%4.18)`i her iki akcigerde lokalize idi. 5 Median sternotorni, 6 segmentektomi, 7 wedge rezeksiyon, 9 lohektomi, 13 transdiafragmatik karaciger kistine miidahale, 1 transdiafragmatik- yolla dalak kistine mildahale, 159 kistotomi + kapitonaj, 10 de-kortikasyon, 4 kistekrom.i yapildi. 4 vakada postoperatif ampiyem ortaya cikti ve tedavi edildi. 1 vaka S011illUM yetmezlikinden kay-hedildi. Niiks grizlenmedi.
In this article, 191 cases were presented who operated in The Thoracic and Cardiovascular Sur-gery Clinic, University of Selcuk between 1987 and 1994. 52.87% of them were male and 47.12% of were female. Most of the patients were 11-20 years of age. 99 of cystes (51.83%) were in right lung, 84 (43.97%) were in left lung and 8(04.17%) of them were in both lungs. Median sternotomy was per-formed in 5 cases, segmentectomy in 6 cases, wedge resection in 7 cases, lohectomy in 9 cases, cystotomy and capitonage in 159 cases, decortication in 10 cases and cystectomy in 4 cases. 13 liver cystes and one spleen cyste were excised via trans-diaphragmatic approach. Empyerna was seen in 4 cases and succesfully treated. Only one case died on respiratory failure. Relapse was not seen in any case.
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Seluk Unıversitesi Tıp Fakultesı İnfeksiyon Hastalıkları Klıni '6ınde Izlenen Akut Vıral Hepatıt Olgularının Degerlendırılmesı
Mehmet Bitirgen, Emel Türk Arıbaş, Ekrem Çopur
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Seluk Unıversitesi Tıp Fakultesı İnfeksiyon Hastalıkları Klıni '6ınde Izlenen Akut Vıral Hepatıt Olgularının Degerlendırılmesı
EvaluatIon Of Cases WIth Acute VIral HepatItIs HospItalIzed In The ClInIc Of InfectIous DIseases, Faculty Of MedIcIne Selcuk UnIversIty
Selcuk Universitesi Tip Fakultesi infeksiyon Has-taliklari Kliniginde 1990-1995 yillarinda yatirilarak izlenen 182 akut viral hepatit olgusu dekerlendirildi. Olgularin % 26.40'inda akut hepatit A, % 69_231iinde akut hepatit B. % 1.62'sinde akut hepatit D (Delta ko infeksiyon ye super infeksiyon) ye % 2_75'inde de akut hepatit C saptandi.
182 cases with acute viral hepatitis hospitalized in the Clinic of Infectious Disease Faculty of Me-dicine. Selcuk University were evaluated between 1990 and 1995 acute viral hepatitis A was detected in 26.40 %, acute viral hepatitis B in 69.23 %, acute viral hepatitis D (Delta co-infection and super-infection) in 1.62 % and acute hepatitis C in 2.75 %.
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Egzersız Stres Testınde St-Segment Yukselmesı Ve Anjıografık Bulgular
Hasan Gök, Bayram Korkut, Gülay Korkmaz, Mehmet Tokaç, V. Gökhan Cin, Hasan Hüseyin Telli
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Egzersız Stres Testınde St-Segment Yukselmesı Ve Anjıografık Bulgular
St Segment ElevatIon DurIng ExercIse Stress Test And AngIographIc FIndIngs
Bu calısmamızda, prospektif olarak, egzersiz stres testi (EST) pozitifligi nedeniyle koroner an-jiografi gerc..ekle§tirilen olgularda ST-segment yuk-selmesinin prevelansint ve EST esnasinda ST-segment yukselmesi gosteren gecirilmic miyokard in-farktilsil (GM!) olan ve olmayan olgulart klinik, EST, anjiografik ye prognostik agdan kar-plaormayt amacladtk. calt§maya 16'si (% 88.8) erkek. 2'si (% 11) kadm 18 olgu altridt (yav ortalantast 54. 1 ±9.9 yil). Olgularm 12'sinde (% 66.6) GM! anamnezi yard:, 6'smda (% 34) GMI yokru. EST pozitifligi nedeniyle koroner anjiografi yapilan 210 olgunun 18'inde (% 8.5) ST segment yiikselmesi teshit edildi. Olgularm 137inde (% 72) anterior, 2'sinde (% I I) inferior. ninde (% 16.6) inferior+anterior derivasyonlarda ST segment yukselmesi helirlendi. , GM! olan 3 olguda patolojik-Q'nun olmadigt de-rivasyonlarda ST-segmenti yukseldi. 9 olguda ise ST-segment yiikselmesi Q-dalgast olan lo-kalizasyonunda geli§ti. GM1 olan olgularm sadece 5'inde (% 41.6) EST esnasinda gogiis agrtst oldu. GM! olmayan olgulartn (n=6, % 100) hepsinde EST'de gqiis agnst oldu ye ciinde anterior. I 'inde
In this study, we aimed to investigate the pre-valence of ST-segment elevation during exercise stress test (EST) in patients who underwent co-ronary angiography because of EST positivity, and to compare the clinical, EST, angiographic and prognostic data of patients with ST-segment ele-vation in EST with and without prior myocardial in-farction (PM1). Eighteen patients with exercise-induced ST-segment elevation were studied (male: 16 (88.8 %), female: 2 (11 %), mean age 54.1±9.9 years). Of these patients 12 had evidence of PM1. The pre-valence of ST elevation was (% 8.5) in 210 patients who underwent coronary angiography because of EST positivity. Thirteen patients (72 %) showed ST elevation in anterior, 2 (11 %) in inferior and 3 (16.6 %) in inferior+anterior leads. Three of PMI (+) patients showed ST elevation remote from pathological-Q wave, when 9 had ST elevation in the PM! localization. On the other hand, angina occured during EST in all patients with PM1 but in only 5 (41.6 %) of PM] (-) group.
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Konya Bolgesı Seker Fabrıkalarında (konya - Eregli - I5 Kazaları Ion Rısk Faktorlerı
Sezai Dikici, Tahir Kemal Şahin, Selma Çivi, Orhan Demireli
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Konya Bolgesı Seker Fabrıkalarında (konya - Eregli - I5 Kazaları Ion Rısk Faktorlerı
The RIsc Factors Of OccupatIonal InjurIes In Sugar FactorIes Of Konya RegIon (konya - EreglI - 11gm)
(MET Konya Bolgesi eker Fabrikalartnda (Konya -Eregli - Ilgin) 1990-1991 yillarinda meydana gelen 4 kazalartni incelemek amactyla yapttgimiz vaka-kontrol tipindeki hu aravirmaya, vaka gruhu olarak iki yilda 4 kazast gecirm4 230 erkek kontrol gruhu olarak da 4 kazast gecirmem4 230 erkek olmak iizere toplam 460 erkek 4ci dahil ed;Imigir. Bire - hir e§legirme ile araprmaya altnan 4- cilerde yaptlan analizlerde, evli 4cilerin hekar 4- cikrden 2.5 kez, hizmet siireleri 2 yam altindaki 4-ilerin kidemleri 2 yildan fazla olanlara gore 5.1 kez, 4in niteliginde makinistlik yapanlartn yardtmct hizmetlere Ore 5.6 kez daha fazla 4 kazast riskine sahip oldugu hulunmuctur. lc kazast gecirenlerin % 51.7'sinin tamirat yaparken kaza ge•irdigi tespit edilm4tir. Turkiye pker iiretiminin % 21 karplayan hOlge eker fahrikalaruntzda 4 kazalanntn hiiyiik •ogunlugunun hasit koruyucu onlemlerin ahn-mastyla onlenehilecegi veya en aza indirilebilecegi sonucuna vat-lift-11pr.
In this case - control study, we examined the oc-cupational injuries which had happened at years of 1990 and 1991 in sugar factories (Konya - Eregli - Nut) of Konya Region. We took 230 male workers who were subjected to an occupational injury during these two years as case group and 230 male workers who were not subjectedto any occupational injuries during these two years as control group. By analy-zing the matched workers who were involved in our study, we found out that in married workers, the risk of occupational injury was 2.5 times higher than the unmarried workers. The workers who had a se-niority of less than two years had a higher oc-cupational injury risk as 5.1 times greater than the workers who had a seniority of more than two years. It was seen that, among the machinists the oc-cupational injury risk was 5.6 times greater than the helper staff It is determined that, 51.7 % of whom subjected to an occupational injury, were subjected to that injury while they were doing repairing. It is concluded that the greatest part of oc-cupational injury could he prevented by taking simp-le preventive measures.
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Ondansetron Ye Droperıdol'un Postoperatıf Bulantı Ye Kusma Uzerıne Etkılerının Karsılastırılması
Sadık Özmen, Lütfi Yavuz, Ali Kart, Sema Tuncer, Ateş Duman
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Ondansetron Ye Droperıdol'un Postoperatıf Bulantı Ye Kusma Uzerıne Etkılerının Karsılastırılması
The ComparIson Of The Effects Of Ondansetron And DroperIdol On PostoperatIve Nausea And VomItIng
Postoperatif tehlikeli komplikasyonla►dan olan bulanti ye kusmanin 4ecitli antiemetik droglarla riskli hastalarda profilaksisi bir cok yap/Ida oneriirnektedir. calqmamizda 58 hastada ondansetron ye droperidol'un postoperatif antiemetik etkilerini 13 saat siireyle kontrol grubuyia karplaprdik. Komplikasyonlar her iic grupta da ecjt oranda (p>0.05) gozlendi. Ancak ondansetron gruhunda ge• donemde (7.-10. saatler), droperidol kullantlanlarda erken donemde (1. -7. saatler) ve kontrol gruhunda ise cok erken donemde (0.-I. saatler) bulanti kusma sikliginda artg gozledik (p<0.05). Bu bulgularimizla, riskli vakalarda ondansetron profilaksisinin yararli oldugu kanaatine vardik.
Prophylactic medication with antiemetic drugs for nausea and vomiting in high risk patients are recomended in may publications. In our study we evaluated the antiemetic actions 13 hours postoperative of ondansetron and droperidol on 58 patients. Complications were similar in all three groups (p>0.05). Nausea and vomiting were more frequent during the 7. and 10. hours in the ondansetron, I. to 7. hours in the droperidol and 0-1 hours in the control groups (p<0.05). With these results we cocluded that ondansetron prophylaxis is effective in high risk patients.
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Kanser Hastalarında Psııkwatrık Semptom Dagılımı
Betül Altuğ, Nazmiye Kaya, Şamil Ecirli, Seyhan Dura, Rahim Kucur
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Kanser Hastalarında Psııkwatrık Semptom Dagılımı
PsychIatrIc Symptom VarIety In Cancer PatIents
Bu calışma 1995 yilmda SUTF Ic Hastaltklart ye Psikiyatri Kliniklerince ortak olarak yaptIdt. Hastaltklart Klinikince kanser tants: konmu,s ye takip edilen 64 hasta caliFmaya aim& Hastalara SCL-90-R uygulandt. Olgularm %21.9 (14 olgu)' unda Genet Semptom Ortalamast > I, %34.4 (22 olgu)'unde somatizasyon belirtileri, %45.3 (29 olgu)'iinde obsesif kompulsif belirtiler, %43.8 (28 olgu)'inde depresif belirtiler, %26.6 (17 olgu)'sinda anksiyete belirtileri bulundu. Bulgular literati& bilgileri ışığında tartışıldı.
This study was carried out together by department of internal medicine and department of psychiatry in Selcuk University Medical School in 1995. 64 cancer patients diagnosed and followed up in internal me-dicine department were assessed and SCL-90-R was performed to the patients in this study. In 21.9% of the patients (14 patients) GSI> I. 34.4% the patients in this study (22 patients) had signs of somatisation, 45.3% (19 patients) had signs of depression and 26.6% (17patients) had signs of anxiety. Findings were discussed in the literature.
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Idrar Yolu Enfeksıyonlarında Ampırık Antıbıyotık Secimi
Salih Hoşoğlu, Bahriye Çümen, Celal Ayaz, Mehmet Faruk Geyik, Mehmet Boşnak
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Idrar Yolu Enfeksıyonlarında Ampırık Antıbıyotık Secimi
EmpIrIcal AntIbIotIcs Treatment In UrInary Tract InfectIons
Diyarbakir Devlet Hastanesi Bakteriyoloji La-boratuvarina 1994 yili icinde idrar kulturu kin On-derilen materyallerden iiretilen aerob hakterilerin antibiyotik duyarliltga araorildi. cali§ma kap-samina alinan toplarn 172 idrar Orneginden 128'inde E.coli, 24'iinde S.aureus ye diger 20'sinde ce#tli bakteriler iiretildi. Izole edilen bakterilerin imipenem (1PM), siprofloksasin (CIP), ofloksasin (OFX), norfloksasin (NOR), sefotaksim (CXM), amoksisilin-klavulanat (AMC), sefiksim (CTX) ye seftazidim'e (CAZ) karp olan direncleri Kirby-Bauer disk diffiizyon yontemiyle araprildi. An-tibiyotik direnci 1PM'e %1.16, C1P'e % 14.53, OFX'e % 15.69, NOR'e % 17.44, CTX'e % 22.67, AMC'a % 23.83, CXM'e % 40.69 ye CAZ'e % 40.69'du. Kinolon grubu antibiyotiklerle iiciincii kupk sefalosporinler direnc acisindan kar-pla§tirildiginda istatistiksel olarak anlamh fork vardi (p<0.001). Idrar yolu enfeksiyonlarinda co-gunlukla antibiyogram sonucu beklenmeden tedavi uygulandigindan bu calipna ampirik tedavi icin yol gnsterici olacaktir.
This investigation was performed in Mic-robiology Laboratory of Diyarbakir State Hospital in 1994. We isolated 172 aerob bacteria from urine specimens and investigated antibacterial sensitivity. The bacteria which were investigated as follows: E. coli 128, S. aureus 24 and the other bacteria 20. The sensitivity of isolated agents to imipenem (1PM), ciprofloxacin (CIP), ofloxacin (OFX), nor-foxacin (NOR), cefataxime (CXM), amoxicilline-clavulanat (AMC), (CTX) and ceftazidime (CAZ) were investigated by Kirby-Bauer disc diffusion method. According to antibiotic susceptibility test the resistance was observed to !PM 1.16 %. CIP 14.53 %, OFX 15.69 %, NOR 17.44 %, CTX 22.67%, AMC 23.83 % CXM 40.69% and CAZ 40.69 %. The difference between Quinolones and Third Generation Cephalosporines were sta-tistically meaningtiil (p<0.001). We suggested this study guedlines for empirical antibiotic treatment in urinary tract infections.
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Dısulfıram'ın (tetraethylthıuram Dısulfıt) Staphylococcus Aureusılar Uzerıne In-Vıtro Etkısı
Naci Kemal Kırca, Bülent Baysal, Fatma Keklikoğlu
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Dısulfıram'ın (tetraethylthıuram Dısulfıt) Staphylococcus Aureusılar Uzerıne In-Vıtro Etkısı
The InhIbItory Effect Of DIsuIfIram On The In VItro Growth Of Staph. Aureus StraIns
Bazi antihiyotiklerin disulfiram benzeri etki gijs-terdigi hilinmektedir. Bu calipnada disulfiramin an-tibiyotik benzeri etkisinin olup olmadigi araq-tirilmivir. 40 Staphylococcus aureus sup iizerinde caliplmq 30 (% 75) siic disulfirama in-vitro duyarli buluntnuour.
Several antibiotics have been reported to have disulfiram-like effects_ In this study we evaluated disulfiram for its antibiotic-like effects. For this pur-pose, we studied several Staph. aureus strains in dis-ulfiram containing discs. Interestingly, we observed that 30 (75 %) of Staph. aureus strains in this study were sensitive to the antibiotic-like effect of disulfiram in vitro.
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Laparaskopik Kolesıstektomı
Şakir Tekin, Adnan Kaynak, Şükrü Bülent Özer, Mehmet ak
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Laparaskopik Kolesıstektomı
LaparoseopIe Choleeystectomy
Ocak 1994 ye temmuz 1995 tarihleri arastnda Seljuk Universitesi Tip Fakiiltesi Genel Cerrahi ABDInda laparoskopik koksistektomi (LK) yaptlan 268 olgu degerlendirildi. 236 hasta biliyer kolik Lie seyreden safra kesesi tap, 32 hasta akut koksistit ta-nisi almo. ilk gruptaki 4 hastada ta§likolesistit ya-runda, yandac hastaltk olarak dalak absesi, dalak kist hidatigi. karaciger sol lobda ye sag overde hasit kist vardi. Tedavileri yapildt. 15 hasta daha ijnceden batin ctmeliyatt gecirmigi. LK 252 hastada began ile yapilirken 16 hastada aciga gecilme zorunlulugu duyuldu. 6 hastada ciddi komplikasyonlar gorilla. Mortalite olmadt, or-talanza ameliyat siiresi 50 dk, hastanede kalma sii-resi 2 giin, normal aktiviteye donme siiresi 1 hafta olarak bulundu. Bu calgmadaki komplikasyon orantnin yiiksek ()imam klinigimizde Llenin yeni uygulanmaya beglanniq olmasina bagh oldugu düşünüldü.
268 cases on which laparoscopic cho-lecystectomy was treated in General Surgical De-partment at the University of Selcuk, Faculty of Me-dical Science between 1994 th January-1995 th June were taken into consideration. 236 patients have de-veloped gallbladder stone which moves along with bilecholic, 32 patients have developed acute cho-lecystitis and 4 patients, because of having de-veloped splenic abcess, splenic eccinococcous cyst, simple cyst at left lobes of the liver, simple cyst at right over were taken into operation. Despite the successful application of la-paroscopic cholecystectomy at 252 patients, 16 pa-tient had necessarly been take into laparotomy. Mortality rate is nil. The operation approximately takes 50 minutes and patients are kept at our hos-pital for nearl 2 days and the patient's recoveries takes a week. Serious complications was observed at 6 patients. We come to the conclusion that the reason for the complications peeing high is that this kind of surgical attempts are very recently applied in our clinic.
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Bogaz Kulturlerınde Ureyen Mıkroorganızmalar Ve Izolasyon Sıklıkları
Mahmut Baykan, Hilal Kart, Bülent Baysal
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Bogaz Kulturlerınde Ureyen Mıkroorganızmalar Ve Izolasyon Sıklıkları
The IsolatIon Rate Of The MIcroorganIsms WhIch Were Isolated From Throat Cultures
Bu calumada, 01 Ocak 1991 ye 31 Aralik 1994 yillari arasinda Selcuk Universitesi Tip Fakiiltesi Hastanesinin deg4ik klinik ye polikliniklerinden gonderilen hastalarin hogaz Ornekleri, bogaz in-feksiyonlarinda etken patojenlerin ye izolasyon sik-tiklaninn saptanmasi amactyla deg erlendirildi. Top-lam 15510 hogaz orneginin 13171'inde (% 85 ) normal hogaz florast bakterileri saptanirken, 2339 (% 15 ) ornekte etken patojen mikroorganizmalar izole edildi. En sik izole edilen patojenler; 603 (% 25) Staphylococcus aureus, 569 (% 24) A grubu beta hemolitik Streptococcus (AGBHS), ye 345 (% 14) Non A Non B grubu beta hemolitik Strep-tococcus olarak hulundu.
In this study, we evaluated throat cultures which come to the University of Selcuk Microbiology Unit among the dates 01 January 1991 and 31 December 1994. We researched the effective pathogen of thro-at infections and their isolation rates. From total 15510 throat samples, 13171 (85 %) of them were normal flora bacteria and 2339 (15 %) of the samp-les, it was isolated the effective pathogen mic-roorganisms. Most frequently isolated pathogens were found; 603 (25 %) Staphylococcus aureus, 569 (24 %) group A beta hemolytic Streptococcus and 345 (14 %) Non A Non B group beta hemolytic Streptococcus.
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Sıgara Wen Ye Icmeyen Genclerde C Vıtamın! Kaynaoı Olan Besın Alımının Kan Ye Idrar C Vitamint Duzeylerıne Etkısının Incelenmesı
Esra Teberdar, Tahir Kemal Şahin, Selma Çivi, Sadık Büyükbaş
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Sıgara Wen Ye Icmeyen Genclerde C Vıtamın! Kaynaoı Olan Besın Alımının Kan Ye Idrar C Vitamint Duzeylerıne Etkısının Incelenmesı
A Study On The E,ffect Of (smoker And Non-Smoker) Young People's NutrItIon Abundant In VI-TamIn C (whom Smoker And Non-Smoker) On Blood And UrIne VItamIn C Levels.
VET Konya Selcuk Universitesi Tip Fakultesi ye Egi-tim Nisan-Mayis 1993 doneminde yaplan bu aravirmada, 18-25 ya§lart arasinda, si-.gara is en 82, sigara ictneyen 163 olmak iizere 245 ogrenciden faydalantlmtpr. Deneklerin sigara icme durumlari ile birlikte, C vitamini kaynagz olan be-sinlerin ahmintn kan ye idrar C vitamini diizeylerine etkisi incelenmgtir. Ara§tirmada, genclerde sigara kullantmtnin kan C vitamini duzeyini dii§iirdiigii saptannuotr. Diyetle yetersiz miktarda C vitamini kaynagi plan besinlerin alinumn, kan C vitamini duzeyindeki der-letici etkisi oldugu tespit edilmitir. C vitamini kay-nagi olan besinlerin ahmtnin artmasi, sigara ken ye icmeyen deneklerin kan C vitamini diizeykrinin art-manna yol agni§tir. Elde edilen hulgular sonucunda, sigara is iminin insan saghgt is in tehlikeli hir sorun oldugu kabul edilmic ve bu sorunun cOzamlenmesi kin acil on-lemlerin alinmast gerektigi ifade edilmiştir.
In the research, which was made in the Medicine and Education faculties of Konya Selguk University between April 1995 and May 1995, 245 students at the age of 18-25 were examined, 82 of whom were smokers, and 163 of whom were non-smokers. In addition to smoking habits, the intake of food con-taining vitamin C and its effect on the blood and urine vitamin C levels were examined. It has been observed that smoking decreased the blood vitamin C level. It has been also observed that intake of poor vitamin C had an important effect on the decrease of the blood vitamin C level. Increase in the uptake of pod rich in vitamin C has cor-relation with the increase in the blood vitamin C level in both smokers and non-smokers. It has been understood that smoking is harmful for the human health and urgent precautions should he taken against it.
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Çocuklarda Nazal Flunıtrazepam Lie Rektal Mıdazolam Premedıkasyonunun Preoperatıf Sedasyon Ye Induksıyon Uzerıne Etkılerının Karılastırılması*
Lütfi Yavuz, Sema Tuncer, Ateş Duman, Alper Yosunkaya, Selmin Ökesli
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Çocuklarda Nazal Flunıtrazepam Lie Rektal Mıdazolam Premedıkasyonunun Preoperatıf Sedasyon Ye Induksıyon Uzerıne Etkılerının Karılastırılması*
ComparIson Of The Effects Of Nasal FlunItrazeparn And Rectal MIdazolam PremedIcatIons On The PreoperatIve SedatIon And InductIon In ChIldren.
1-12 yac arasr cocuklarda premedikasyon amacryla henzodiazepin gruhu ilaclardan flunitrazeparm nazal, miclazolamt da rektal kullarup, preoperatif anksiyete lizerine etkisini aravirchk. 1_ Gruha (NF) nazal 0.03 mg.kg-1 flunitrazepam, Gruha (RM) rektal 0_45 mg.kg-I midazolam operasyondan 30 dk once verildi. Premedikasyon ye induksiyon oncesinde Subjektif Sedasyon Anksiyete Sayrsal Skoriamasi (SSASS) yapriarak degerler kaydedildi, Isoflurane lie inhalasyon indiikslyonu siirecinde hemodinamik parametreler ye solunumsal problemler gozlenerek kaydediMi. NF gruhunda komplikasyonlar daha cok gozlendi (% 58.33), Premedikasyon oncesi SSASS skorlarr her iki grupta da qitken; NF gruhunda indiiksiyon oncesi sedasyon yerine anksiyetede arm, RII4 gruhunda ise sedasyon amp gozlendi. Her iki grupta da indiiksiyon siiresinde Kalp Atm flizz (KAH) arty sr olugu (p<0_05). NF gruhunda indiiksiyonun 1. dk da cok anlamh (p<0.001), 5. dk da anlamb (p<0_05) Sistolik Arter Basincr (SAB) artqf gozlendi_ RM gruhunda 1. dk da anlamb (p<0.05) Diastolik Arter Banner (DAB) amp oldu. Sonuc• olarak nazal flunitrazepanun c..ocuklarada uygun hir premedikasyon afam olamayacagrna, rektal midazolanun ise etkin ve giivenilir hir ajar oldugit kantstna vardtk.
We evaluated the effects of nasal administered flunitrazepam and rectal midazolam on preoperative anxiety in children of ages 1 to 12. 0.03 mg.kg-1 nasal fhtnitrazepam for group I (NF) and 0.45 mg.kg"/ rectal midazolam (RM) was given to group 30 min before the operation. The Subjective Numerical Anxiety - Sedation Scores (SNAS) were recorded before premedication and induction. Cardiovascular variables and respiratory complications were recorded during inhalational induction with isoflurane. Complications were more frequent in the NF group (% 58.33), although the SNAS scores were similar before premedication in both groups, before induction the anxiety scores in the NI,' group and the sedation scores in RM group were increased. A rise in heart rate (HR) was recorded in both of the groups (p<0.05), In the NF group a significant increase at the fifth minute (p<0.05) and a very significant increase during the first minute (p<0.001) occured in the systolic blood pressures (SBP), in the RM group a significant rise in diastolic blood pressure (DBP) was recorded during the first minute. As a result, we have concluded that while nasal)) administered flunitrazepam is not a favorable premedication agent. rectal midazolam is effective and safe in children for premedication.
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Asetılkolın Ile Kasılan Role Kobay Ve Tan/san Mıde Fundusunda Pınaverıum'un Etkısı Ve Bunun Kalsıyum Ile Ilıskısı
Ekrem Çiçek, H. İbrahim Karabacak, Esra Kısmet Atalık
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Asetılkolın Ile Kasılan Role Kobay Ve Tan/san Mıde Fundusunda Pınaverıum'un Etkısı Ve Bunun Kalsıyum Ile Ilıskısı
The Effect Of PInaverIum On Isolated GuInea-PIg And RabbIt Stomach Fundus Contracted WIth AcetylcholIne And Its RelatIon WIth CalcIum
Izole kobay ye Cav an mile fundusunda yaptlan bu in vitro calqmada, kalsiyumsuz ortamda 10-4 M asetilkohn (ACh) ile kasilan dokular fizerine konsantrasyonda uygulanan kalsiyumla (10-4 -10-2 M) elde edilen cevaplara pinaveriumun etkisi 077 mM Na2 EDTA iceren Ca+2 'suz ortamda 10-4 M ACh ile elde edilen cevaplar, kiimillatif kan-santrasyanda Ca+2 ilavesiyle doza bagunli bir anlamh olarak arm. Ortamda pinaverium (10-5 M) varliginda her iki dokuda da maksimum cevap anlamh olarak azaldt. Kobay mide fundusunda pi-naveriuma bagli inhibisyonun taq.an mide fun-dusuna gore anlamli olarak yiiksek ()Mugu goriildii (P<(L05)_ Elde edilen bulgular, pinaveriumun muhtemelen her iki dokuda da ekstraseliller Ca+2 giri ini inhibe edebilecet ini gostermektedir.
In this in vitro study, by using Ca-I-2 -free me-dium, the effect of pinaverium on acetylcholine (ACh) responses induced by cumulative addition. of Ca+2 (10-4 - 10-2 M) was investigated in isolated gu-inea pig and rabbit stomach fimdus. The responses induced with 104 M ACh, Ca+2 -free medium containing 0.77 mM Na7 EDTA, sho-wed a dose-dependent and significant increase by addition of cumulative concentration of Cal-2 . In the presence of pinaverium (10-5M), the maximum response decreased significantly in both pre-parations. It was showed that the inhibition induced by pinaverium was higher in guinea-pig stomach fundus than in rabbit stomach ftmdus (P<0.05). The results suggest that extracellular Ca+2 - int-lux can be inhibited by pinaverium in both pre-parations.
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Konya Bolgesı Seker Fabrıkalarında (konya - Eregli Ilgin) 15 Kazalarının De6erlendırilmesı
Sezai Dikici, Tahir Kemal Şahin, Selma Çivi, Orhan Demireli
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Konya Bolgesı Seker Fabrıkalarında (konya - Eregli Ilgin) 15 Kazalarının De6erlendırilmesı
EvaluatIon Of OccupatIonal InjurIes In Sugar FactorIes Of Konya DIstrIct (konya-EreklI-LlgIn)
Konya Biilgesi 5.eker Fabrikalarrnda (Konya -Eregli - Ilgin) 1990-1991 yillarinda meydana gelen kazalartni incelemek ama•iyla 1992 yilinda yap-tigimtz bu araitirma, is kazasi ge•irmif 230 i§ci ve 4 kazasi gecirmemil 230 i§c.i olmak lizere toplam 460 erkek iizerinde kazasi ge•iren i§•ilerden ulacahilen 87 ici ile yiizylize ilverenle arasinda kazalarin olu§ nedenleri ve onlenebilirligi ko-nusunda gorialmesine ragmen. turn kazalaremn basil linlemlerle onlenehilecegi so-nucuna varilmunr.
In this study, we examined the occupational in-juries which had happened at years of 1990 and 1991 in sugar factories of Konya district (Konya-Ereg li-llgin). We investigated 230 workers who were subjected to an occupational injury and 230 workers who were not subjected to any occupational injuries from their registration cards. We in-terviewed with 87 workers who were available among these subjected ones. There were some dif-feren•ies between these 87 workers' registration card informations and their answers about the cause of occupational injuries. However, it is concluded that the greatest part of occupational injuries could he prevented by taking simple preventive measures.
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Buyuk Amelıyatlarda Aprotının'ın Yerı
Sami Ceran, Cevat Özpınar, Mehmet Yeniterzi, Tahir Yüksek, Ufuk Özergin, Sadık Özmen, Mehmet Kılıç, Hasan Solak
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Buyuk Amelıyatlarda Aprotının'ın Yerı
The Role Of AprotInIn In The Long Term OperatIons.
Bir proteaz inhibitorii olan aprotinin kar-diopulmoner by passlarda kullandmaktachr. Ap-rotinin yabanct yiizeyk temas eden plateletlerin fanksiyonlarmt koruyarak kan kaybuu azaltugt tah-thin edilmektedir.lik doz aprotinin kullantlan 15 kardiak ye torasik cerrahi hastasmda aprotinin to-raks operasyonlarinda da drenajt azalttigi Aprotinin yabanct yiizeyle temas etmemiy olan plateletlerin fonkisyonlarint da korumaktadtr.
Aprotinin, the serine proteaz inhibitor, has been used in cardiopulmonary bypasses. It is supposed to reduce blood loss by preserve platelet functions which contacts foreign surfaces. 15 patients un-dergoing thoracic or cardiac operations were given low dose aprotinin. Its blood saver effect were seen a thoracic operations as effective as cardiac ones. IT seems that aprotinin can preserve the functions of platelets which dont contact any foreign surfaces.
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Uzun Surelı Antıkonvulzan Kullanımına Baglı Bır Osteomalazı Olgusu
O. Cem Türeli, Ömer Faruk Şendur, Önder Murat Özerbil
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Uzun Surelı Antıkonvulzan Kullanımına Baglı Bır Osteomalazı Olgusu
OsteomalacIa Due To Long-Term An-TIconvulsant Therapy (a Case Report).
Uzun süreli antikonviilzan kullanI111111111 os-teomalaziye yol acabildigi ortaya konalmuoir. Sag kalcadan dize kadar yayrlan agri yakmmass ile pa-liklinigimize bapuran hastanin cekilen pelvis gra-fisinde her iki femur hoynunda Looser zonlari sap-tantrultzr. Bu nedenle antikonviilzan ilac kullananlann peryodik olarak osteomalazi yo-Minden takip edilmeleri uygun olur karusindaym.
It is known that anticolvulsant drugs cause os-teomalacia. As patient who suffered of leg pain were questioned and examined, we noticed that he has used an anticolvulsant drug (diphenylhydantion) for a long time by the reason of seizure. We found bi-laterally Looser zones in femur necks when ra-diological examination were carried out. Obviously it is useful to follow up the patients periodically who use anticolvulsant drugs.
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Dev Kıstık Hıgromalarda Tedavı : Üç Olgu Nedenıyle
Adnan Abasıyanık, Alaaddin Dilsiz, Engin Günel, Burhan Köseoğlu
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Dev Kıstık Hıgromalarda Tedavı : Üç Olgu Nedenıyle
Treatment Of GIant CystIc Hygroma: Three Cases Report
Kistik higroma lenfatik kiikenli benign bir yondur. Lenfatiklerde olulan konjenital mal-formasyon nedeniyle lenfatik akim bloke ol-maktadir. Bazen de aim sekestrasyonlar sonucu dev kistik higromalar olu§maktadir. Bunlar kongu do-kuMri ve vital organlarl infiltre etmektedir. Boylece solunum yollarina bast. hemoraji ve sepsis gibi ciddi komplikasyonlara yol armaktathr. Der kistik hig-romalarin total cerrahi eksizyonlari bazen miimkiin olamamaktadtr. Bu nedenle cerrahive alternatif te-davi cekilleri araprilmaktadir. Bu califmada Seljuk Universitesi Tip Fakiiltesi cocuk Cerrahisi nde tedavi edilmic servikal (n=1) ve ser-vikoaksiller (n=2) yerle imfi dev kistik higromalt olgu sunulmultur.
Cystic hygroma is a hamartomatou.s lesion of lymphatic origins. It is a benign tumor that appear to arise from congenital malformation of the lym-phatic resulting in blockage of lymphatic flow. It has a tendency to infiltrate and surround adjacent tissues and vital organs. Respiratory distress, hem-orrhage and sepsis are major complications of giant cystic hygroma. Total exicion of this benign tumor is sometimes impossible. Alternative treatment to sur-gery is investigated. In this report three cases of the cervical (n=1) and cervicoaxillary (n=2) cystic hy-groma that were treated at the Department of ►e-diatric. Surgery, Faculty of Medicine, Selcuk Uni-versity were presented
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Bir Arcus Aorta Varyasyonu
Semih Diyarbakırlı, Atıf Aydınlıoğlu, Papatya Keleş
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Bir Arcus Aorta Varyasyonu
A VarIatIon Of AortIc Arch
45 yavnda erkek kadavrada yaptlan dis-seksiyonda, arteria carotis communis sinistranin truncus brachiocephalicus ile birlikte, ayrica arteria vertebralis sinistra ile arteria subclavia sinistranin truncus ceklinde arcus aortadan ciktigr tesbit edildi. Bu varyasyon literatfir bulgulari ile karplaftrrildt.
During the dissection performed on a cadaver of a 45 years old man, it was observed that the left ver-tebral artery arise from the aortic arch shared with the left subclavian artery and truncus brachio ce-phalicus (with regularly branches) arise from the aortic arch with the left carotid artery. This vari-ation was compared with findings of literature.
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Forestıer Hastalıgı Idyopatik Skeletal Hiperostozis)
O. Cem Türeli, Ömer Faruk Şendur, Önder Murat Özerbil
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Forestıer Hastalıgı Idyopatik Skeletal Hiperostozis)
ForestIer's DIsease (dIffuse IdIopathIc Skeletal HyperostosIs)
Senil ankilozan hiperostozis veya spondilosis hi-perostotika da denilen Forestier hastaligt genellikle spinal. bazen de ekstraspinal yerleOmli, ya§ant ka-litesini hozmayan, tedaviye iyi cevap veren hir has-Bu yazida kliniimize hel agrtst nedeniyle bapurati ye vertebra yerlepnli Difiiz Idyopatik Ske-letal Hiperostozis (DISH) tanisi alan hir olgu hil-dirmektedir.
Forestier's disease which is known senile ank-ylosing hyperostosis or spondylosis hyperostotica is generally localized spinal, sometimes extraspinal. The disease does not effect the quality of life and has a good response to treatment. In this article a Dif-fuse idiopathic Skeletal Hyperostosis (DISH) case who has low hack pain and localized in vertebrae is presented.
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Tıp Meslegınde Sır Saklama (meslek Sırrı)
Orhan Demireli
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Tıp Meslegınde Sır Saklama (meslek Sırrı)
Secretary In The Medıcal Professıon (professIonal Secret)
Deontoloji tüzüğünün 4. maddesinde, tabip ye diş tabibinin meslek ye sanatını icra ederken 0- rendigi hastaya ait sirlari kanuni mecburiyet ol-madikya ifa edemiyecegi, tibbi toplantilarda takdim edilen veya yayinlarda bahis konusu olan vakalarda hastanin kimliginin aciklanamayacagi belirtilmektedir.
In the 4th article of the deontology charter, it is stated that the physician and the dentist cannot perform the secrets of the patient that he / she has taken while performing his profession, unless there is a legal obligation, that the identity of the patient cannot be disclosed in cases that are presented at medical meetings or are mentioned in publications.
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Serbest Radıkallerın Yalanmadakı Rolü
Hüseyin Vural, İdris Akkuş, M. Akif Bor
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Serbest Radıkallerın Yalanmadakı Rolü
The Role Of Free Radıcals In Lıe
Serbest radikaller son yillarda en cok tizerinde durulan ye ara§tirmalarin yogunla§tigi bir konudur. Serbest radikallerin hticresel kaynaklan, rol oy-nadiklari reaksiyonlar ve serbest radikallere kar§i hacresel savunma mekanizmalarinin ayikhga ka-vu§masi, buglin bilinrneyen pek yok klinik du-rumlarin patogenezine ayikhk getirecektir .
Free radicals are an issue that has been emphasized most in recent years and research has been intensified. The cellular sources of free radicals, their role-playing reactions, and the emergence of haectal defense mechanisms against free radicals will impede the pathogenesis of few clinical conditions that are currently unknown.
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Sutun Onemı Ve Brusellozıs İle İlıskisi
Semin Güler, Tahir Kemal Şahin
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Sutun Onemı Ve Brusellozıs İle İlıskisi
The Importance Of Column And Its Relatıonshıp Wıth Brucellosıs
Süt, organizmanin gelişmesi ye yaşamını devam ettirebilmesi icin gerekli olan hayati besin un-surlannin hepsini iceren ideal ye dogal bir icecektir
Milk is an ideal and natural drink that contains all the vital nutrient flour-wastes necessary for the organism to grow and survive.
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Transfuzyon Tedavısı
Aziz Polat, Ali Keskin
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Transfuzyon Tedavısı
TransfusIon Therapy
Son zamanlarda iransfiizyon tedavisinde kom-ponent tedavisi on Plana caring olup spesifik kan komponent replasmant yaptImaktadir. Eritrosit, trombosit. plazma veya spesifik plazma proteinleri gibi kan komponentleri tam kan yerine sikhkla ye et-kili olarak kullantlabilir. Bu makalede eritrosit, trombosit ye graniilosit transfiluonu endikasyonlart ve izlenecek stratejiler tartışılmıştır.
More recently, component therapy broadened the application of transfusion therapy from blood volume support to the specific replacement of blood components. An individual component of blood such as red blood cells, platelets, plasma, or specific plasma proteins, may often be used effectively in place of whole blood. This issue describes in-dications and strategies for red cell, platelet and granulocyte transfusions.
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