Selçuk Tıp Dergisi Arşiv

In this study, 479 criminal children were sent to Forensic Medicine Divisional Directorateship for their discrimination and mental capacities to be sulted for child correction institutions. Twenty five children were out of the age range of examination of disc-rimination and mental capacity. Remaining 454 sub-jects were largely males (96.5 %). The large per-centage of criminal ages were 15 (39.7 %) and 14 (33.9 %) years of age. The most attempted erime was steeling and burglary (54.4 %). Of those 96.6 % were the age of discrimination and mental capacity and knowing attempted to the crimes. Twenty sub-jects, although they had the ages older than 11 years old, were below the discrimination and mental ca-pacity level. Among them two (10.0 %) were mentally retarded. Ten subjects (50.0 %) were inclined to at-tempt criminal temptations due ta their fawer socio-economic cultural type of living. Of those, six (30.0 %) of thern were lacking behind the psychobiological developments and unaware of the judgement of their criminal acts. The remaining two (10.0 %) subjects were deaf and dumb, and they were considered to have low level of discriminative ability and mental ca-pacity. This study when compared ta similar studles carried out else where in Turkey, it can be concluded that the type of erime attempted and the ratio of disc-riminative and mental capacity were of similar.

The aim of this in vitro study was ta investigate the inhibitory and relaxant effects of sodium channel blockers, tetrodotoxin (TTX, 10-8 - 10-6 M), flecainide (10-6 - 3x10-4 M) and pilsicainide (10-6 - 3x104 M), on both electrical field stimulation (EFS)- and car-bachol-induced contractions in the rabbit trachea. In addition, the role of nitric oxide or cyclooxygenase products synthesized from epithelium in the pre- and postsynaptic effects of these agents was in-vestigated. EFS (20 sec at 40-50 V, 20 Hz, 1 msec) pro-duced reproducible contractions in the tracheal strips. Al! of the sodium channel blockers used in-hibited EFS-induced contraction in a concentration-dependent manner. The rank order of potency for in-hibition of EFS-induced response was TTX > fle-cainide > pilsicainide. TTX did not influence the car-bachol-induced contractions. Carbachol-induced contractions of tracheal strips were dose-dependently inhibited by preincubation with the other sodium channel blockers and flecainide was more potent than pilsicainide. However, in tracheal strips precontracted with carbachol, the relaxant effects of sodium channel blockers did not differ from each other. TTX, flecainide and pilsicainide did not alter the baseline tension. Preincubation with in-domethacine or L-NAME altered nen-her the post-juctional inhibitory and relaxant effects of the sodium channel blockers nor their inhibitory effects on EFS-induced contractions. In conclusion, all sodium channel blockers used inhibited EFS-induced contractions of the rabbit trac-hea. Flecainide and pilsicainide inhibited carbachol-induced contractions while TTX did not influence them. Pre- and postsynaptic effects of the sodium channel blockers were not changed by in-domethacine or L-NAME.

The effects of penicilin G(F'), amoxicilin + kla-vulanic acid (AMC), + ampicilin + sulbactam (SAM), cefadroxil (CFR), erythromycin (E), clarithromycin (CLR) and azithromycin (AZM) to GABHS isolated from throat smear were analyzed using Kirby-Bauer disk diffusion technique. In-vitro, P sensitivity in 220 strains found in 100%. The resistance were E in 6%, CLR in 7%, AZM in 8%, and CFR in 9% white the re-sistance against AMC and SAM were 0% P, AMC and SAM are stili the first choise for the treatment of GABHS infections.

Fractures of the clavic!e are common and make up a high percentage among the skeletal system tra-uma. They are well managed by conservative met-hods. 496 clavicular fractures of 493 patients were diagnosed between 1993 and 1997 in our dinle 357 of thern were men and 136 women. Average age was 38.5 (18-78). Years in 207 of them right side was affected and in 289 left. 3 of the cases had bi-lateral involvement. Conservative treatment included velpeau dressing or figure of eight bandage. 82 of the patients were lost to follow-up after the first exa-mination. Remaining 414 fractures of 411 cases were followed up at least 1.5 months 3 nonunions (%0.7) were detected_ Conservative treatment re-sulted in % 99.3 of union.

Between 1985 and 1998 three men with breast cancer vere treated in our depantnent, Physlcal exa-mination and treatment results of these patients are presented. Follow up period was 13 years in one pa-tient, more than two years in the other two patients. We preferred radical mastectorny in these three pa-tients because of the small volume of the breast, and the close lacotion of the pectoral fascia in men.

A case of very large condyloma acuminatum lo-cated in inguinal region in a 62 years old male 40 years history was treated by surgical excision and split thickness skin graft. Altough it had very Tong his-tory there was no malign transformation in histo-pathological examination. We presented it because of its unusual size and tong history without malign transformation.

Mediastinal extravasation is a rare mechanical complication of longterm subclavian vere cat-heterization. It's probable due ta the chronic irritation of catheter on the vessel wall. In this article, a case with the diagnosis of biliary tract fistula whom subc-lavian vein catheterization was applied with the pur-pose of TPN was presented.

Growth and development of a organism vere re-gulated by growth hormones and growth factors along the axis of hypothalarnus-pituitaıy. It was exp-ressed by lots of researchers that arnang these fac-tors, insulin like growth factors take role in diagnosis and treatment of diseases. fn this review, know-ledges abouf chemical structures and functions of re-ceptors and binding proteins of these factors have been reviewed.