Selçuk Tıp Dergisi Arşiv

İn this study that was performed on spontaneous abortions refferred to Department of Medicial Genetics of Medical Faculty of Selçuk University, detection of the incidence and type of chromosomal abnormalities in spontaneous abortions was aimed. With this aim; the specimens from 54 spontaneous abortions were successfully cultured and karyotyped by using conventional cytogenetic techniques. 27.8 % of karyotyped abortions were found to have a chromosomal abnormality. Autosomal trisomy was the predominant chromosomal abnormality and accounted for 53.4 % ali abnormal abortions, followed by poliploidy (26.6 %) and monosomy X (20.0 %). Trisomies were consist of trisomy 15, 18 and 21. One mosaic marker was observed in one aborted specimen. Detected poliploidy comprised two triploidy and two tetraploidy. The obtained findings revealed that chromosomal abnormalities have an important role on etiology of the spontaneous abortions and that for this reason cytogenetic examination of aborted specimens is useful for parent of abortions and for physicians.

Triple test of population of Konya in prenatal diagnosis İn this study, a MoM value were calculated for the triple test at 16-20 weeks of pregnancies. The aim of this investigation was to help diagnosis of Down syndrome and neural tube defect Median levels of these three analyt were calculated for 16-20 weeks of pregnancy These values were combined with age and individual risk values were determined. As a result of this investigation triple test ıs acheupreliable and ımportant tecnique for detection of NTD and Down syndrome and must be used generally.

İn this study, anterior, middle and posterior clinoid processes were studied in total of 62 skulls belonging to Anatomy departments of different universities. When it comes to speak about the existance of caroticoclinoid foramen emerglng from the commissure of anterior and middle clinoid processes, whether any changes in the dimensions of optic canal ever happened was studied. As result, İn 15 (24.19%) out of 62 skulls caroticoclinoid foramen were found bilaterally. İn two (3.2%) only in the right side and five (8.06%) for the left side. Statistically, there were no significant dlfferences has been found betvveen the dimensions of the optic canal of skulls having caroticoclinoid foramen and those not having.

İn this study, experimental hypothyroidism in rats was induced using 6-propyl-2-tiouracyl (PTU) and its effects on kidney, glomerule and tubules structure were investigated at microscopic level. İn the experiments, 60 days old 12 female rats which weighted 200-250 gr were used. The rats were separeted into two groups. To one group, 10 mg/kg day PTU was introduced intraperitoneally for 15 days. To other group which was used as a control group %0.9 physiological solution (PS) was injected intraperitoneally for 15 days.. İn the renal structure investigated by light and electron microscope, it was observed that internal and external medulla were similar to those of the control group. Moreover, some expansion in glomerül capillaries of cortex, plumpness and expansion in capsule cavity were observed. Particularly, basal folding in proximal tubule was found to be evident. Likevvise, increase in intercelluler spaces and formation of a vacuolize view were found. İt was found that there was no any damage in glomerule filtration barrier at thin structure level. İt was also found that there not no any difference in basal lamina which was similar to the control group.

Specimens obtained with sinüs aspiration from 21 patients with chronic sinusitis were microbiologically examined. Fifteen microorganisms from 10 (47.6%) patients were isolated as causative agents. From the samples of five patients only one type of microorganism isolated but from the samples of the other patients 2 different types of microorganisms isolated. 12 Of the microorganisms isolated were identified aerobes, 2 of them as yeasts and one of them anaerobe. Bacterias were İdentified as alpha hemolytic Streptococcus, Neisseria spp., Diphteroid rod, Streptococcus pneumoniae, coagulase negative Staphylococcus, Enterobacter cloacae, Proteus mirabilis and fungus were Candida albicans.

Larygoscopy and endotracheal intubation are known to increase blood pressure and heart rate by release of cathecholamines from the sympathetic nervous system. Our study aimed to evaluate, remifentamTs effect on this response. This study was performed on 40 ASA l-ll class patients aged between 19-45 years planned for laparoscopic elective surgery. Patients were randomised in two groups. Ali patients received 0.03 mg kg-1 midazolam IV. After Standard monitorisation (ECG, noninvasive blood pressure, heart rate, SpO2) 1.5 pg kg-1 remifentanil was given to group I and 25 pg kg-1 alfentanil to group II patients as bolus injection. Standard anesthesia induction was made 1 minute after these drugs. (Propofol 2 mg kg-1, succinylcholine 1.5 mg kg-1). Measurements (sistolic blood pressure, diastolic blood pressure, heart rate) were performed: in the beginning (t0), before propofol (tğ, before laryngoscopy (t2), 1and 3 minutes after the endotracheal intubation (t3, t4), 1 minutes after skin inc'ıslon / trochar insertion (t5). Statistical comparisons were made by student t tests. İn each of the two groups t1t t2, t3, t4, t5 values (systolic, diastolic blood pressures, and heart rate) were signrficantly decreased (p<0.05). The response to tracheal intubation (t3, t4) and skin incision (t5) were less in remifentanil group than in alfentanil group (p<0.05). As a result, we think that remifentanil can be preferred to alfentanil because remifentanil can supress the haemodynamic response sufficiently the larygoscopy endotracheal intubation

İn this study, totally 203 patients with iron deficiency anemia who had been hospitalised and became therapy in our department between January 1996-June 2000 were examined. Of the patients143 were female and 60 were male, mean age was 45.09+17.11 year in females and 58.43+14.75 year in male. The mean values of erythrocyte were 3.673.007±677.929/mm3 İn females, 3.520.333±780.210/mm3 in males, haemoglobin was 8.49+2.2 g/dl in females, 7.42±2.3 g/dl in males, hematocrit was 27.1+6.3 % İn females, 23.9+6.3 % in males, mean corpusculer volüme was 70.2±9.3 fl in female, 66.9+10.4 fl in males, serum iron was 27.66±8.5 mcg/dl in females, 25.97+8 mcg/dl in males, serum iron binding capacity was 383.94±56.11 mcg/dl in females, 389.72±48.4 mcg/dl in males, serum ferritin was 4.73+3.3 ng/ml in females, 5.05±3.3 ng/ml in males. Chronic gastrointestinal bleeding and gynecologic bleeding were found to be the most commen causes of iron deficiency anemia in females vvhereas chronic gastrointestinal bleeding in males.

Aim: We aimed to report the long-term results of the patients undergone posterior preperitoneal tension-free mesh hernioplasty operation for inguinal hernia. Patients and Methods: IVe icnluded in this study 624 patients undergone posterior preperitoneal tension-free mesh hernioplasty operation for inguinal hernia betvveen October 1992 and June 2000. The patients were invited for control in the first and third postoperative months and yearly. The patients who did not come to control were asked by telephone and letter if they had any recurrences and problem with their operation. The patients lost their communication with us after the operation were excluded from this study. The patients were examined and evaluated for urinary retention, bleeding, spermatic cord edeme, wound infection, neuralgia and recurrence in the early and late postoperative periods. Results: 584 of the patients were men and 40 were women. The patients were follovved 37.4 months (range: 6-108 months) after the operation. We found 1.8% recurrence, 0.3%> bleeding, 2.7%> infection, 4.2% spermatic cord edeme, 0.6% neuralgia and 0%> urinary retention ratio. Conclusion: We concluded that, posterior preperitoneal tension-free mesh hernioplasty operation is a safe method with low morbidity and recurrence rate in inguinal hernia repair.

Cartilaginous tumors of larynx are rare, but should be suspected in elderly patients with persistent hoarseness, dyspnea, or dysphagia after malign epithelial tumors has been disproved. 250 cases have been reported in the literatüre. These tumors were investigated by revievved of the literatüre.

Melkersson- Rosenthal syndrome (MRS) is a rare disorder of unknovvn etiopathogenesis. This syndrome is characterized by a triad of recurrent orofacial edema, relapsing facial palsy, and scrotal tongue. İn this report a 24 year old man with the typical clinical symptoms and signs of MRS is reported. İn addition, the literatüre on MRS is revievved with respect to incidence, etiology, clinical features, pathology, diagnosis and treatment.

Localized solitary fibrous tumor of the pleura is a rarely seen tumor of the pleura beyond It’s unclear histogenesis, differantiation, malignity potential, and clinical behaviour. They are usually seen in 5-8. decades and more than 50 % of the cases are asymptomatic. The most important prognostic factors are the size, cellularity, and resectability of the tumor. For these reasons in surgical treatment wide resection is advised. İn this article, two female patients who were 48 and 53 year-old are reported with the diagnosis of localized solitary fibrous tumor originated from diaphragmatic pleura. The tumors removed successfully and the patients did not have any complication postoperatively. Because of the rareness of localized solitary fibrous tumor of the pleura it is thought to be worth reporting.

A fifty two year old woman sustaining bilateral hand injurles after a traffic accident was admitted to our clinic. She had right thumb amputation from the carpometacarpal level, tendon and skin loss in the right hand secönd finger, loss of the 2-3 extensor tendons and the overlying dorsal skin in the left hand. Reconstruction in a single session was planned and palmaris longus tendons from both hands were taken and used as intercalary grafts for extensor tendon losses after which the skin loss was covered with a radial forearm flap. Afterwards, the second injured finger in the right hand was taken and pollicisized using the Buck Gramcko technique. At the last follow-up examination 8 months after the injury, she was able to pick up small objects and grip large and heavy objects using her right hand. The range of motion of the wrist and the fingers of the left hand was completely restored. The importance of treatment design tailored individually for each patient was stressed in this case.

Post-traumatic pseudocysts of lung are rarely seen complications of blunt chest traumas. Usually spontaneous resolution is seen in 2- 4 months after trauma, but a few of them are get into abscess or tension cyst formation after Progressive expansion and in these circumstances surgical resection is indicated. Radiologically they are frequently seen as thin-wall cysts consisting air-liquid levels. Unless they had a drainage bronchus in the beginning they are usually seen as pulmonary hematomas due to hemorrhage. 14/e herein report 15, 17, 47 and 49 year old four cases who were hospitalized for blunt chest traumas in our clinic. Three of them were male and one was female. Ali the pseudocysts localized in the right lung, and in two of the case the cysts resolved in a period of 2.5 and 4 months with medical treatment. But in two cases surgical treatment needed for their Progressive expansions.