Selçuk Tıp Dergisi Arşiv

Objective: The aim of this study was to investigate the probable changes which may occur on the respiratory functions of the female patients undergone laparoscopic cholecystectomy. Methods: Twenty laparoscopic cholecystectomy applied patients aged 18 to 50 (average 34.6 ± 10.0) years were taken into this study. Pre- and postoperative first and seventh day respiratory function tests were performed with Sensormedics PFT System 2400. PCA (patient controlled analgesia) apparatus was used to determine the pain feelings of the patients during the first postoperative 24 hours. Meperidin was used for analgesia. Analyses of the results were evaluated with variance analyses of the differences betvveen measurements and repeated measurements. Bonferroni corrected paired t test at 0.05 level was used for the determination of the difference betvveen dublicate measurements. Results: On the first postoperative day compared to the preoperative levels a reduction on FVC, FEVj, PEF, MVV, VC, TLC, FRC and DLCO values and an increase on RV values of the patients were observed. On the seventh day of the operation compared to the first day an increase on FVC, FEVj, PEF, MVV, VC, TLC, FRC and DLCO values and a reduction on RV values of the patients were observed. VVhile PEF values on the seventh day compared to preoperative value were decreased there was no important change on the other PFT values. Conclusion: İt is concluded that the changes on the respiratory function tests of the female patients follovving laparoscopic cholecystectomy mostly returns to normal on the 7th day of the application.

İn our study, kVe have aimed to search the findings seen on the tissue specimens taken from the liver, kidney, ovary, testis and pancreas of many rats that have been poisoned by long- term high doses of florid. Twenty rats which belong to VVistar Albino species were being eçually separated into two groups, one is as the experimental group, the other as the control group [10 (5 male + 5 female) + 10 (5 male + 5 female)]. For a 17 weeks time, drinking water consisting of 1 ppm florid to control group and consisting of 150 ppm florid to experimental group has been given. Pieces taken from the tissue specimens of the liver, kidney, spleen, ovary, testis and pancreas were being examined under the light microscope. İn the experimental group, the following findings were being obtained: İn peripheral lobule of the liver, focal sinusoidal dilatations, in the portal area, lymphocyte infiltration; in hepatocytes a liftle hydropic and vacuolar degeneration; in the kidney either in proximal or distal tubule, a liftle hydropic degeneration were being determined. There hasn’t been seen any pathology in the spleen, ovary, testis and pancreas sections taken from the experimental group. As a result, it was determined that high doses of florid causes minimal structural changes primarily in the liver tissue and then in the kidneys, besides it has no considerable effect on the testis, ovary, spleen and pancreas tissue.

Objective: Comparison of the respiratory functions were aimed in this study in female Behcet’s patients whether with or without pathological pulmonary lesions according to high resolution computerized tomography (HRCT) evalutions. Methods: 29 female patients aged between 19 to 54 (average 37.0 ± 9.5) years and as control group 20 healthy female aged 19 to 50 (40.5 ± 8.3)years were taken into the study. Patients and control group individuals were physically inspected, HRCT films were taken and pulmonary function tests (PFT) through a spirometer were determined. Patients were divided into two group according to HRCT results as HRCT (+) and HRCT (-). HRCT (+) group patients (n=11) vvere aged 28 to 54 (average 39.9 ± 8.1)years and HRCT (-) group (n=18) vvere 19 to 50 (aver­ age 35.2 ± 10.1) years. İn ali groups the determinations of FVC, FEVj, PEp25-75%’ PEF, VC, RV, FRC, DLCO and DLCO/VA values vvere performed. Analysis of the results vvere carried out by preferred variance analysis and Tukey HSD tests. Results: A statistically important difference was not observed when the PFT values vvere compared betvveen HRCT (+) and HRCT (-) patients for the obtained results and the percentage rate to expected results. When the PFT values vvere compared for both HRCT (+) and HRCT (-) patients group with the control group separately though there was no statistical difference betvveen the best values but only a statistical decrease in DLCO/VA values (p<0.01) was observed betvveen the percentage rate to espected results. Conclusion: İt may be said that though there is a pulmonary restriction in Behcet’s disease but this restriction has no relation with respiratory functions. Thus it vvill be useful to perform pulmonary function tests in both vvith or vvithout pathological findings through HRCT evaluation in order to obtain some Information about respiratory functions of Behcet’s patients. Additionally vve presume even when the results of the pulmonary functions tests are normal though some pathological changes in HRCT should be considered HRCT investigations may be useful to follovv the disease. HRCT investigations may be useful to follovv the disease.

Purpose: İn this study, we aimed to determine the measurements and the relation betvveen craniofacial morpho- logy and orbita in full term, prematüre nevvborns and nevvborn with low birth vveight. Materials and method: We vvere studied 60 prematüre nevvborns (Male 30, Female 30) who vvere aged betvveen 32 and 37 post menstrual vveek, and 60 full term nevvborns (Male 30, Female 30), and 60 nevvborn with low birth vveight (Male 30, Female 30). İn ali cases, head circumference, head length, head vvidth, face height, face vvidth, orbita height, orbita vvidth, oropalpebral length and cantal index vvere measured. Average of measurements of cranio-facial and orbita vvere calculated in the ali cases. Results: The measurements of craniofacial and orbita vvere statistically significantly dif- ferent betvveen prematüre and full term infants in vvhom it was greater than prematüre infants (p<0.001). The re vvere differences in the measurements of craniofacial and orbita betvveen sexes. A significant positive correlation betvveen the craniofacial and orbita dimensions was found in prematüre nevvborns and nevvborn with low birth vveight (p<0.001). There was negative correlation betvveen head vvidth and orbita vvidth in full term nevvborns. Conclusions: VVith more expressions of the parameter of craniofacial and orbita at prematüre and full term nevv­ borns and nevvborn with lovv birth vveight, more Information about individual variations vvill be given. Knovvledge about normal variations in craniofacial and orbita dimensions can help in diagnosis of pathologies or anomaly of crania-facial skeleton development.

Classic kernicterus or the neurotoxicity of neonatal hyperbilirubinemia is known well, but the pathological jaundice may show itself vary different subtle neurological dysfunction at the some patients. 159 patients male 61.1 %, female 38.9 %, mean age, 24.6±13.11 months, peak bilirubin levels 20.07±4.85 mg/dl uho had therapied neona­ tal hyperbilirubinemia were studied. Newborns with serum total bilirubin levels of 15a-19.9 mg/dl in 97 patients (group I), 20-24.9 mg/dl in 41 patients (group II), 25-29.9 mg/dl in 15 patients (group III), and > 30 mg/dl in six patients (group IV) were accepted. V/e performed Denver Test ali patients and performed odiogram test 46 patients. We determined that subtle neurological abnormalities and high bilirubin levels correlate each other. However, we showed that group I and II had some problematic findings lesser degree than group III and IV. Management of jaundice in the Asian nevvborn is stili problematic and we need a lot of studies about toxic biliru­ bin levels.

İn this study, the prevalence of H.pylori-lgG antibody was investigated in 83 hemodialysis (HD) and 30 CAPD patients and compared with those of 45 healthy control group. İn determination of IgG antibody against H.pylori enzyme immunoassay ELİSA method was used. Mean ages were 46.2+17.4 and 44.6+15.7 years and dialysis durations were 35.4+ 36.9 months and 20.2+18 months in HD and CAPD patients respectively. Age of control group was 49.4+15.3 (18-80) years. H. Pylori-antibody was positive in 36 HD patients (43.4 %), in 9 CAPD patients (30 %) and in 19 healthy Controls (42.2 %). Hp-lgG antibody positivity in HD and CAPD patients was not statistically different from control subjects. İn conclusion, there is no assosiation between Hp-lgG antibody posi­ tivity and age, sex, dyspeptic symptoms two groups. İn this patients Hp IgG positivity should not be evaluated with- out endoscopic and.histopathologic findings.

Aim: To determine the eficacyandpossible complications of autulogous serum application in patients with dry eye. Methods: 27patients, nine with Sjögren’s syndrome, were included in the study. İn addition to their previous med- ications, patients were administered drops which were prepared by diluting their own serum to 20% with şaline. Symptoms, tear characteristics and ocular surface parameters were evaluated. Results: Statistlcally significant improvements in symptoms and ocular surface parameters were observed in 40% of the patients at the 15th day and in 85% of the patients at the 30th day. Tear characteristics did not show any diffference throughout the study. Although cultures revealed contamination in three patients, no clinically significant infection or any other complication was encountered. Conclusion: Autologous serum applications can be an efficient and safe adjunct treatment for dry eye patients who do not show improvement with other medications.

183 cases with supratentorial aneurysm were operated on in Neurosurgery Department, Selçuk University Meram Medical School betvveen March 1987 and September 2002. İn the present study we aimed to discuss 183 intracra- nial supratentorial aneurysm cases, according to their location, clinical features, treatment modalities, mortality and morbidity rates. The series were evaluated through the review of literatüre and presented.

Asthma is one ofthe commonest diseases in children and adults İn many countries. The prevalence of asthma has dramatically increased in recent years. The development of asthma depend on an interaction between genetic factors, environmental exposure to allergens, and nonspesific adjuvant factors such as tobacco smoke, air pollu- tion, and vira! infections. These factors initiates a series of immunological changes, resulting in airvvay inflamma- tion. The airvvay inflammatory process is characterized by chronic eosinophilic and Th2 type lymphocytic infiltra- tion. Although the knovvledge about asthma pathogenesis has increased, the prevalence of asthma has not decreased. Therefore, the asthma stili is a threat for the society’s health at the beginning of the 21 st century.

De novo 46:XY,t(13;20)(q22;p13) karyotype was detected in a 27 year old congenital deafness case who was referred to our laboratory because of reproductive wastage. Effect of gamets with unbalanced karyotypes which dependent on discussed balanced reciprocal translocation on reproductive vvastage and probable relationship between this balanced reciprocal translocation and congenital deafness were evaluated consldering the compari- son with literatüre.

İn a patient who applied to our outpatient clinic with productive coughing and exertional dyspne vvith a long time history, we established Kartagener’s syndrome. That’s why this syndrome is rare and easly confused with other pulmonary diseases we are presenting this case.

Many different aproaches were reported for the reconstruction of columella defects that local flaps through microvascular tissue transfer. There was a columella defects in 22 years old male patient because of the explo- sion of bomb and the reconstruction was not thought by a local flap owing to large scar tissues next to the defect. After the dissectlon of wide adhesion of the septum nasi spongostan tampons were put into new plane. Then 2x1,5 cm diameter skin island flap with angular artery pedicul was prepared on the right nasolabial skin and transferred to the defect in order to the reconstruction of columella. The flap was folded and sutured. İt was made the flap thin by defatting 3 weeks later. The result was acceptable aesthetically. The results and short operative time for this flap were thought us that it is an alternatlve to the microvascular reconstruction and morbidity of the donor area was acceptable.