Selçuk Tıp Dergisi Arşiv

Neurogenic tumors ocur at all part of the body but most common site is the posterior mediastinum in thorax. In this study, the patients with neurogenic tumor were evaluated clinical and radiological signs in our hospital between January 1999 and December 2003. Of thirty patients were (11 male and 19 female) their range aged from 20 to 70 mean 41.7±11.8. Histological types were 17 (%57) neurofibromas. 7(23%) schwannomas, 4(13%) ganglioneurinomas, 2(7%) malign schwannomas. Twenty-four (80%) of neurogenic tumors were in posterior mediastinum and the others were in different areas in thorax.

Objective: The aim of this study is to determine the frequency of the patients with onychomycosis who have admitted to our clinic. Materials and method: 771 patients aged 18 years and over presented to Dermatology Clinic of Meram Medical Faculty of Selcuk University between October 2004 – January 2005 were included into the study. Age, sex and education level of the patients were noted. Nail samples were taken for diagnosis in our laboratory. Direct microscopic examinaiton and culture were performed. Chi-square test and student t test were used for statistical analysis. Results: Onychomycosis was detected in 67 cases (8.7%), of whom 43 (64.1%) were male and 24(35.9%) were female. The presence of onychomycosis was found to correlate significantly with increasing age (p<0.05), male gender (p<0.05) and low education level (p<0.05). Conclusion: We detected the frequency of onychomycosis as 8.6% in our patients. We consider that occurance rate of onychomycosis may decrease in our region when informative educational measures related to with protection are performed.

Objective: Oxidative stress is defined as the event that the concentration of reactive oxygen species (ROS) formed in tissue or cells exceeding the antioxidant capacity. Long duration oxydative stress predisposes to cancer development. In this study, the role of oxydative stress in colorectal cancers was searched. Material and Methods: 17 patients withcolorectal cancer operated in Ankara University, Faculty of Medicine, Department of Surgical Oncology and Ankara Numune Training and Research Hospital between 2000-2001 were included in the study. During the operation, 1cm3 of mucosa was harvested from the tumoral and neighbouring healthy tissue just following the extraction of specimen. Malondialdehyde (MDA), Superoxide dismutase (SOD), Catalase (CAT) and Glutatione peroxydase (GPX) levels were measured in these tissue samples. Results: Concentration of free oxygen radicals in tumoral and healthy normal tissues were found to be statistically non-different. Conclusion: Oxidative stress in tumoral tissue of colorectal cancers was not different from the normal tissue.

Tuberculosis (TBC) is an infection that rarely seen in the first year of maximum immunosuppression. Beacuase of its rarity we aimed to present a case of TBC that developed after renal transplantation in our newly established transplantation unit. A live donor renal transplantation was performed on a 45 years old man who was complaining of chronic renal failure for four years and on hemodialysis for two years. There was no signs of TBC in the physical examination, preoperative laboratory investigation and past medical history of the patient. Prednisolone, MMF, FK-506 combination and in the 1st and 4th day Basiliximab were performed as immunosuppressive protocol. In 1 st postoperative month, there was a cavernous lesion in the left upper zone on chest x-ray. Antituberculosis treatment was started according to a positive sputum culture for TBC bacili. After twelve months of antituberculosis treatment there was a clinical and laboratory improvement and the treatment was ceased accordingly. Because of its frequent past history in our country, TBC is aserious disease that should be kept in mind and dealt with carefully in patients undergoing renal transplantation.

Two cases of morphea which developed after hepatitis B vaccination at the sides of injection were presented. One of these two patients was a 25 years old female. She referred to our clinic with complaints of brownish spots and hardening on external side of her right arm. In her history she said that she was given hepatitis-B vaccination a year ago, on the thickened parts of her arm, twice with 4 weeks internal. Itching, discoloration and hardening started on these regions 3-4 months later, especially inceasing with exposure to sun. The other case was male and 23 years old. He referred to our clinic with complaints of discoloration, regional hardening, hair fall on the upper part of his right arm. He said that he was given two hepatitis B vaccination 8 months ago with 4 weeks interval. Two months after the innoculation he had the mentioned complaints over the innoculated regions of his arm. Incisional biopsy was taken from both of two cases. Histophathologic examinaton results were found accord with morphea. According to clinic prognosis, plaque and slowly progressive type morphea was found in the female patient and lineer and rapidly progressive type morphea was found in the male patient. Systemic involvement was not determined in both of the two patients. The local and/or systemic treatments were begun to both of the patients.

The cardiovascular involvement is the majör cause of mortality in the scorpion envenomation. Cardiac enzymes should be measured if patients with scorpion envenoming have symptoms related to cardiovascular system accompanied with local pain. Serum level of troponin I is a highly specific fort he myocardial injury. It may be allow early establishing of the cardiac involvement and starting to treatment. The using of troponin I as a follow-up criterion in the scorpion envenoming with cardiac involvement may be prevent from events that will ocur later. We presented a 7-year-old boy with scorpion envenoming.