Selçuk Tıp Dergisi Arşiv

Aim: Hepatitis B virus infection is a very important health problem in our country. In this regard, we evaluated the children who were inspected in our outpatient clinics for Hepatitis B virus seropositivity. We aimed to join the children who were seronegative in the immunization program. Material and method: A total of 297 children between the ages of 3 months and 18 years who were inspected in the General Pediatric Outpatient Clinics of Meram Medical Faculty except for jaundice between July 2005 and December 2005 were evaluated. The children were divided into two groups as 3 months-7years and 8-18 years. After getting permission from parents, 3 cc venous blood samples were collected from all of the children. The serological markers of Hepatitis B virus were studied by Enzyme-Linked Immunosorbent Assay Method in the microbiology laboratories of Meram Medical Faculty. The statistical analysis was performed by SPSS 10.0 program. Results: Anti-HBs positivity were found in 143 ( 48,1 %) of 297 children. One hundred seventeen (81,8 %) of those children were vaccinated while 26 (17,5 %) of them had experienced the infection. Five children (%1,6) had HBsAg positivity. The ratios of children who were vaccinated were 66,4 % in 3 months-7years group and 11,0 % in 8-18 years group, respectively. The ratio of children who were vaccinated was 39,3 % in all children. Conclusion: Although Hepatitis B vaccination is a part of our National Immunization Program, the seropositivity of our region is not as much as it is expected. In this study, we found that the people in our region are not well-informed about the necessity of vaccination against Hepatitis B virus infection, and attention is called to the importance of our job in this point.

Aim: This study was designed to evaluate whether Saccharomyces boulardii (S. boulardii ) is effective on the bacterial colonization of perineal and periurethral areas in children and could be useful in protective treatment in children with recurrent urinary tract infections. Material and method: Fifty four children were included the study. Perineal and periurethral area cultures provided from each of these children were inoculated into the aerobic cultures seperately. Having been orally given only a single dose of 250 mg S. Boulardii per day for ten days, cultures were repeated. Results: Having been administered S. Boulardii, the number of the cultures which yielded Escherichia coli in both perineal and periurethral areas were found to be decreased significantly. No other uropathogens such as Klebsiella and Proteus were detected to be decreased. Conclusion: This study showed that S. Boulardii administration could be useful in the prevention of urinary tract infection recurrences.

Aim: Renal biopsy is performed for the diagnosis and the decision of treatment of renal parenchymal diseases. The aim of this study was to evauate the clinicopathological findings of kidney biopsies. Material and Method: 78 percutan renal biopsies were performed by ultrasonography in our institution during the period between January 2000 and December 2006. Results: The most common renal biopsy indication was nephrotic syndrome (n:39, 50%). Other indications were association of nephrotic and nephritic syndrome (n:14, 18%) and nephritic syndrome (n:7, 9%). The most mikroskocommon nephropathy was mesangial proliferative glomerulonephritis (n:15, 19%) which was followed by Henoch Schonlein purpura nephritis (n:14, 18%), focal segmental glomerulosclerosis (n:8, 10%) and lupus nephritis (n:8, 10%). Primary glomerular diseases (n:48, 62%) is more frequent than secondary glomeruler diseases (n:30, 38%). Conclusion: The present study which evaluated 78 renal biopsies showed that nephrotic syndrome was the most common indication for renal biopsy. Histopathologically, the most frequent nephropathy was mesangial proliferative glomerulonephritis. These results suggest that renal biyopsy results in children can show regional variances and have a fairly different distrubition from those of the adults.

Aim: Renal stone disease is a frequently recurrent disease. Among the renal stone diseases 25–35% is localized to lower pole. Despite different treatments of the lower caliceal stones, partial nephrectomy is assumed to decrease the rate of recurrence. Material and Method: In this study fifty-seven patients, (29 with lower pole nephrectomy and 28 with pyelolithotomy, nephrolithotomy and pyelonephrolithotomy) who were surgically treated for their lower caliceal stones, were re-evaluatnefed in our clinic retrospectively. Infundibulopelvic angle, infundibulum length and diameter were measured by standard IVP according to the renal anatomy definition made by Sampaio et al. The mean follow-up period for all the above mentioned patients was 79 months. Results: Whereas the mean infundibulopelvic angle of the patients, treated with partial nephrectomy, increased from 57 degrees preoperatively to 108 degrees postoperatively, the angle of the patients treated with pyelolithotomy, nephrolithotomy and pyelonephrolithotomy did not change. During the follow-up period, the recurrence rate in the patients, treated with partial nephrectomy, was in 78 months 10 percent, but in the patients; treated with pyelolithotomy, nephrolithotomy and pyelonephrolithotomy, in 80 months 21 percent. Conclusion: Partial nephrectomy decreases the recurrence rate of lower pole renal stones through eliminating the anatomical factors that cause stone formation.

Aim: The purpose of this study is to compare the effects of different anti-adhesion Materials in Preventing Postsurgical peritoneal adhesion. Material and Method: 60 rats from Wistar Albino spiece that weights 250-300 g and about 10-11 ages are used in the study. They were separated into 5 groups. The rats were operated after Kethamine HCL anesthesia. In all rats, a midline laparatomy was done, in a 4 cm length. To the right side of the abdominal wall, 2 cm along 10 parellel incision were applied. To the left side of it, a peritoneum layer was incised as 2x2 cm2. The abdominal wall was sutured with 3/0 silk by continue method. Group I: Control group, Group II: 3X3 cm2 in size Chitin layers (Suprofilm®) were placed on the incision areas. Group III: 3X3 cm2 in size Na-Hyaluronat / Carboxymethylcellulose layers (Seprafilm®) were placed on the incision areas. Group IV: To the abdominal cavity, 25 % diluted 2 cc Na-Hyaluronat gel was poured, Group V: 15mg/kg metilprednizolon was injected as I.M. On the 11th day of Research, under Ketamine anesthesia, abdominal wall opened and the adhesions were scored according to Granat Score. From all groups of rats, blood samples were taken. On the samples, Hb, AST, BUN and Albumin levels were studied. Results: The Adhesion frequency In Group I, was defined on the right abdominal wall as 82%, on the left as 91%, In Group II, on the right as 8.3%, on the left as 25%, In Group III, on the right as 17%, on the left as 33%, In Group IV, on the right as 50%, on the left as 58%, In Group V, on the right as 50%, on the left as 42%. The adhesion grade in groups was defined as; Group I: 2.63±1.22, Group II: 0.58±0.66, Group III: 1.08±1.08, Group IV: 1.41±1.44, Group V: 1.41±1.50. The adhesion phase in all study groups was found meaningfully low compared to the control group as p<0.05. Besides, the adhesion grade of Suprofilm® group was found meaningfully low compared to the other groups as p<0.05. A meaningful difference was not observed among Serologic and hematological parameters in all groups as P>0.05. Conclusion: Chitin meaningfully decreases the postoperative peritoneal adhesion frequency and adhesion grade on Rats. Referencing this result, it has been understood that Chitin is much more effective than local and systemic anti-adhesive methods.

Aim: Familial Mediterranean fever, is the most common and well known disease in hereditary periodic fever syndromes at the present time. In this review we summarized the disease, which was seen frequently in our country, and newly treatment methods. Main findings: Familial Mediterranean fever was described in a Jewish girl in 1908. Generally it was seen in Armenians, Sefaradian Jew, Arabians and Anatolian Turks. Pathogenesis of the disease was not clear. Characteristic feature of the disease is acute fever attacks accompanied with abdominal pain, chest pain and joint pain. The most important complication is type AA amiloidosis. There is no specific laboratory or radiological finding. Colchicum which is used in the treatment, decreases frequency of attacks and prevents from development of amiloidosis. Result: Aproximately 1/4 patients are resistive to colchicum treatment. There are some studies which shows adding interferon a, selective seratonine reuptake inhibitors and biological agents to the treatment are effective in these patients.

Aim: In this study, it is aimed to evaluate a complex and rare variation on branches of femoral artery and to review related literature. Case report: During routine dissections in laboratory of the Department of Anatomy, it is determined that deep femoral artery, medial femoral circumflex artery and lateral femoral circumflex artery had originated from femoral artery in the right thigh of 65-yearold cadaver. Conclusion: Studies related with the variations on femoral artery and its branches may be information source in preventing complications during surgical approachs and especially invasive radiologic procedures like angiography.

Aim: Spinal arteriovenous malformation is a rare pathology located in the dura along the spinal canal. Multi-detector computed tomographic (MDCT) angiography is a recently developed imaging technique. We present findings of magnetic resonance (MR) imaging and multi-detector computed tomographic angiography in 16-year-old patient with spinal arteriovenous malformations. Case report: MR images showed signal voids dilated vessels at the surface of the spinal cord at C1-2 level. Also, multi-detector computed tomographic angiography demontrated dilated varix-like vessels. The patient was diagnosed as having a spinal arteriovenous malformation. Result: Multi-detector computed tomographic angiography can be a non-invasive usefulness technique in detect the spinal arteriovenous malformatios.