Selçuk Tıp Dergisi Arşiv

Aim: In the study where antibiotic resistance of Pseudomonas aeruginosa (P. aeruginosa) strains were aimed to be investigated. Material and method: In the study 130 P.aeruginosa strains isolated from various samples as materials were utilized. Result: Isolated strains were mainly provided from the intensive care unit (60%), the pediatry department (16.2%), and the otorhinolaryngology department (10%). As a result of the sensitivity tests performed for P. aeruginosa strains, the most resistance was provided with gentamicin (75.4%), tobramycin (64.6%), and imipenem(50%). Conclusion: Consequently, it was determined in our study that antimicrobial resistance of P. Aeruginosa strains be decreased, except gentamicin compared to previous years.

Aim: To evaluate the effect of EA application at 2 Hz and diet restriction on the levels of serum beta endorphin, ACTH and cortisol in obese women. Material and Method: EA application and diet restriction was applied on 22 women who had the mean age of 40.95±5.08 and Body Mass Index (BMI) of 33.18±2.23 and only diet restriction was performed on 22 women who had the mean age of 43.09±3.52 and BMI 33.77±2.61. EA was performed on ear points of Hungry, Shenmen and Stomach and body points of KB 4, KB 11, Mi 25, Mi 36, Mi 44, Kc 3 and Da 3 once a week to ear and body points and twice a week only body points for 30 minutes for a 20 days period. Diet restriction was organized for 20 days to give a daily 1400 kcal diet. Results: Weight loss of 3,83% was observed with EA and diet application whereas 3.05% loss was observed with diet restriction alone. Comparison of effects of ACTH, cortisol and beta endorphin on body weigths of the patients in the groups of EA and diet application and diet restriction alone were made with Mann Whitney U test. Additionally the differences between the mean values of basic variables also compared with Mann Whitneyu test. An increase at the weight loss was observed in EA and diet group compared to the diet restriction group alone (p<0.001). Similarly when the differences were compared between the groups significant increases were observed in the levels of serum ACTH (p<0.01), cortisol (p< 0.05) and beta endorphin (p<0.001) in the EA and diet group compared to the diet group alone. Conclusion: It was observed that EA application at the frequency of 2 Hz in addition to diet restriction caused more weight loss than the diet restriction alone in obese individuals. This may be due to the lipolytic effect of increased beta endorphin and ACTH with EA application.

Aim: The aim of this study is to evaluate the outcomes of the patients with uncompleted treatment of TB, their demographical properties and to determine the reasons. Material and Method: This descriptive study was carried out throughout Konya in 2001. Total 1979 cases undergoing TB treatment were included in the study. It was established that 164 (%8.3) of the cases taking TB treatment had given up treatment too early. All these cases were interviewed face to face at their addresses registered in their files. This interview included clinical irregation, PPT application, pulmonary X-ray exemination and collection of sputum for ARB. Results: The mean age of the tuberculosis patients was 36.8±16.5 yrs in male and 38.6±19.1 yrs in female (P>0.05). Among the 1979 cases taking tbc treatment, 8.3% gave up the treatment. This rate was 21.6% among the cases whose treatment began in hospital, and 4.5% among the cases of dispensaries. 40.6 % of the patients was illiterate. 38.7 % of them did not have social security. The relatives of 39.4 % cases had a tuberculosis history. There was accompanying illness in 36.8 % of the patients. 61.9 % of the males and 14.3% of the females were smokers. Conclusion: We believe that general economical development, better education level, regular administration and follow-up systems and efforts to provide a better communication with patients may positively affect the results of efforts against the tuberculosis.

Aim: In this retrospective study, our patients with nephrotic syndrome (NS) were evaluated according to age, sex, etiology, response to steroid, prognosis, and compared with national data and the literature. Material and method: 141 children with nephrotic syndrome (NS) who admitted to the Department of Pediatric Nephrology of Selcuk University between January 2000 and December 2006 were assessed. Patients were classified into two groups according to etiology as primary and secondary NS. Results: 59% of the patients were male and 41% of them were female. Male/female ratio was 1.44, and median age was 9 (0.3-18.5) years. It is observed that 81.5% of the cases had primary and 18.5% had secondary NS. 67 of the patients with primary NS were male and 48 of them were female. Median age was 8 (0.3-18) years. 16 of the patients with secondary NS were male and 10 of them were female. Median age was 14 (7.5-18.5) years. Of patients with primary NS, 76.5% had steroid-responsive, and 22.6% steroide resistant. %64.8 of the patients with steroid responsive NS developed one and more relapses. Percentage of rare and frequent relapses were 3.4% and 61.3%, respectively. Our results showed that mesangioproliferative glomerulonephritis (MesPGN) was the most common histopathologic diagnosis, 15 (45%) of the 31 biopsied patients with primary NS were found to have MesPGN. Henoch Schonlein purpura nephritis was diagnosed in 14 (53.8%) patients and it was the most common cause of secondary NS. As a result, NS frequency and response to rate of steroid therapy are similar to present literature finding. However, frequent relaps ratio was lower than the others studies. Conclusion: We think that further research including more patients population and multiple center and control studies to investigate NS events to reveal causes of concerning with regional, national or race differences at the childhood period is warranted.

Aim: Our aim is to investigate the relation between the increase of abdominal pressure and abdominal compartmant syndrome Material and Method: 61 patients admitted to Selçuk Univercity Meram Medical Faculty Emergency Service with diagnosis of acute abdomen were included in this study. The diagnosis were; 25 cases ileus, 13 cases acute pancreatitis, 11 cases mesentery ischemia seviand 12 cases with intestinal perforations. In all cases urine bladder pressures were recorded as the reflection of abdominal pressure. Meanwhile pH, PaCO2, PaO2, SGPT , SGOT, urea and creatinin levels were measured in venous and arterial blood samples. The procedure was repeated consequently 24, 48 and 72 hours. The correlation between abdominal pressure increase and these parameters were evaluated. Results: Increase in abdominal pressure has negative effects on renal, pulmonary and liver organ systems. Renal function effected by 10 cm H2O pressure and was obviously affected after 20 cm H2O pressure. The increase of abdominal pressure causes respiratory alcholosis; at initial time and hypoxia, hypercarbia, metabolic acidosis and respiratory insuffiency at the late period. Liver enzyms were recorded at high level in abdominal pressure increase. Conclusion: Urine bladder pressure is reflecting abdominal pressure. The incerase of abdominal pressure has positive correlation with urea, creatinin, SGOT, SGPT, and PaCO2 levels and negative correlation with PaO2 and pH levels.

Aim: The aim of this review is to evaluate recent literature regarding effects of nutrition on fetal development. Main findings: Previous studies show that maternal factors such as age, nutrition, and stress are able to have negative effects on fetal development during pregnancy. The role of maternal nutrition on human pregnancy is still unclear but undoubtedly crucial. The dietary recommendations for pregnant women before and during pregnancy are similar to those for other adults, with a few exceptions. The main recommendation is to keep a healthy and balanced diet; however, there are some specific recommendations related to daily supplementation of minerals and vitamins during pregnancy to reduce the risk of birth defects. Maternal nutritional status during the period of conception is an important determinant of fetal growth and development. The relationship between maternal nutrition and low birth weight, intrauterine growth retardation, and spontaneous abortus are reported in the literature. Furthermore, maternal nutritional factors associated with different kinds of birth defects such as neural tube defects, oral cleft, cardiovascular, central neural, respiratory, and urinary system defects. Result: Therefore, further researchs are need for the effects of maternal nutrition on fetal growth

Aim: Epidermoid cyst is an uncommon ectoderm originated benign cyst. Although intracranial epidermoid cyst may commonly occur in the cerebellopontine angle and chiasma opticum, it can be detected in cerebral hemispheres as well as intraventricular area. Syringomyelia, a progressive hydrodynamic disorder of spinal canal usually occurs in cervical region although it can be seen in thoracic and lomber portion of the spinal cord. Case report: We describe a patient with syringomyelia associated with posterior fossa located epidermoid cyst. Siringomyelia has been spontaneously regressed after the removal of the posterior fossa epidermoid cyst. Conclusion: Primary intervention to spinal cord cavitations must be avoided because it can be spontaneously regressed after the removal of the posterior fossa tumor.

Aim: Tarsorraphy is formation of lids adhesion by approaching the eyelids. Not only eyelid’s anatomy but also functions can be damaged because of using suture during adhesion. The aim of our study is to adhese the eyelid in a safe method easily without disturbing the tarsal structures, eyelid architecture and function. Case report: The silicone rod was used in the process of tarsorraphy application for eleven patients whose ages were ranging from 10 to 65 in 2001-2005 in our clinic. Tarsorraphy was used without any complications in postoperative follow-up period in all patients. Conclusion: Silicone rod is an alternative tarsorraphy material in order to prevent the damage to eyelids and tarsal structures.