Selçuk Tıp Dergisi Arşiv

\r\n Objective: Early diagnosis of cutaneous squamous cell carcinomas (CSCC) is the most important factor affecting prognosis and most patients have a good prognosis. Some patients defined as high-risk group have high rates of regional recurrence and distant metastasis, and follow an aggressive course. In addition, recently numerous studies have being performed for determining the importance of sentinel lymph node sampling, and sentinel lymph node (SLN) positivity has been associated with a poor prognosis. In this study, we aimed to determine prognostic importance of SLN outcomes in patients with high-risk patients diagnosed with CSCC.

\r\n Patients & Methods: A total of 29 patients who underwent excisional operation in various body regions with the diagnosis of CSCC between 2009 and 2017, with available complete clinical and pathologic data were included in the study. At least 9-month clinical follow-up results, high risk factors and sentinel lymph node biopsy outcomes of the patients were recorded and analyzed. Patients with at least one of the American Joint Committee on Cancer (AJCC) criteria were considered as high-risk group.

\r\n Results: Twenty-five of the 29 CSCC patients were in the high-risk group. SLN positivity rate was 12% (n: 3/25) in the high-risk CSCC patients, all patients in the low-risk group had negative SLNs. All patients with SLN positive underwent local complementary lymphadenectomy, and all of these patients were re-operated due to recurrence. The rate of recurrence was found as 100% (n= 3/3) in high-risk CSCC patients with positive SLN, and 18% (n= 4/22) in high-risk CSCC patients with negative SLN. High recurrence rates (41.6%) and SLN positivity were observed in patients with hand-foot localizations.

\r\n Conclusion: High rates of local recurrence may be seen during progression of the disease in SLN positive patients. Hand-foot localization of CSCCs can be considered as a high risk factor regardless of a tumor diameter should be above 0.6 cm.

 Postpartum haemorrhage (PPH) which is the first cause of maternal mortality in our country is responsible for about 25% of maternal deaths in the world . While PPH is defined as loss of 500 ml or more of blood from the genital tract within 24 hours of thebirth of a baby, severe PPH is blood loss exceeding 1,000 mL. The most common causes are uterine atony, genital tract injuries and placental retention. Many methods are used such as effective implementation of the uterine fundus massage, the use of agents which myometrium contact, hypogastric and/or uterine artery ligation or embolization in its treatment. Despite this, PPH is the primer cause of maternal death in our country. To reduce maternal mortality rates caused by dependence of PPH,  evidence-based approaches are important in treatment and care. Pharmacological, surgical approaches and various applications for the third stage of labour in the prevention and treatment of PPH are used. But there are no evidence-based studies at adequate levels for all treatment. The clinical data in a large part of the PPH/therapeutic approach are limited. Therefore, it is intended in this article to determine the current approaches related to the prevention of postpartum haemorrhage and to inform health professionals about the adequacy of the initiatives implemented.

A rare cause of acute abdomen; appendiceal neuroma. Case report

ABSTRACT

    Acute abdomen refers to nontraumatic pathologies of abdominal origin which are characterized by sudden-onset abdominal pain. In most cases the cause of pain is a pathological condition requiring urgent surgical intervention. Acute appendicitis is the most common indication for surgical intervention in patients presenting to emergency department with acute abdomen. Obstruction of appendiceal lumen has been widely accepted as the precipitating factor in the pathophysiology of acute appendicitis. It usually develops as a result of food or feces particles entering into and obstructing appendiceal lumen, leading to inflammation and swelling of regional lymph nodes. Luminal obstruction results in overproduction of bacteria, excessive mucus secretion, and increased intraluminal pressure. Some studies in recent years have suggested a neural component in the pathophysiology of this condition. Such cases may present with various diagnoses such as obliterated appendix, fibrous obliteration, appendiceal neuroma, and neurogenic appendicitis. In this paper we present a case operated with the initial diagnosis of appendicitis and histopathologically diagnosed with appendiceal neuroma, a rare cause of acute abdomen.

 Moyamoya disease is an entity, which is caused by obstruction or stenosis in the area between the internal carotid artery, and anterior and middle cerebral arteries, identified angiographically, and does not have an exactly known etiology. The most frequent symptoms of onset are hemorrhage in adults and ischemia in children. In this paper, we present a case of Moyamoya disease which was diagnosed with a 21 year old male patient who was admitted to our emergency department with headache, nausea vomiting and left hemiparasi complaints and whose radiological findings showed right basal ganglia hemorrhage.