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Aim: Executive function deficits are very common in attention deficit hyperactivity disorders (ADHD).
Recent studies suggest that common mechanisms in the pathophysiology of obesity and ADHD may be
related to impulse control and executive functions. This study aimed to compare the executive functions
and self-esteem levels of children and adolescents with ADHD with and without overweight/obesity. The
study also aimed to examine the relationships between overweight/obesity, executive functions, ADHD
and self-esteem in children and adolescents.
Patients and Method: Participants included 71 children/adolescents (mean age = 16.12±1.71; age range=
12-18 years; 71.83% males) with ADHD who applied to Gazi University Child and Adolescent Psychiatry
outpatient clinics between March 2021 and April 2022 and did not use any medication. Participants
completed the Executive Functions Behavior Evaluation Inventory Scale (parent form), Conners Parent
Rating Scale-Revised Short Form and Rosenberg Self-Esteem Scale .
Results: Results showed that hyperactivity symptoms and working memory function were significant
predictors of self-esteem in adolescents with ADHD. In addition, when adolescents with ADHD were
compared according to their overweight/obesity level, significant differences were found between the
groups in working memory and planning/organization functions. However, no difference was found
between the groups in terms of self-esteem and ADHD severity.
Conclusion: The findings suggest that working memory and hyperactivity symptom severity may play an
important role in understanding the self-esteem of adolescents with ADHD. While no difference was found
in terms of self-esteem and ADHD clinic in adolescents diagnosed with ADHD according to overweight/
obesity status, differences in working memory and planning/organization skills suggest that executive
functions play a critical role in overweight/obesity in ADHD.

Aim: The purpose of this study is to examine whether there is a difference between the sense of movement
of the glenohumeral joint of the dominant extremity and the sense of movement of the non-dominant
extremity.
Patientss and Methods: In the study, 20 healthy and sedentary, volunteer participants (10 males,
10 females) who did not have shoulder problems were included. Mean age of the participants were
23.60±3.64 years. Data collection were performed between July 6, 2020 and August 3, 2020. The sense
of movement of the dominant and non-dominant extremities of the glenohumeral joint was measured for
the participants. The measurement of sense of movement was done by using an isokinetic dynamometer
by measuring the passive sense of movement threshold value at an angular speed of 0.1°/s. The sense
of movement measurement was performed towards four directions: from 0° (0°-IR) and from 30° (30°-IR)
to internal rotation direction, and from 0° (0°-ER) and from 30 ° (30°-ER) to external rotation direction.
Results: The sense of movement of the participants for internal rotation at angles and directions of 0°-IR,
30°-IR were respectively 1.27±0.47, 1.30±0.45, and for external rotation at angles and directions of 0°-
ER, 30°-ER were respectively 1.25±0.39, 1.41±0.32 for the dominant side extremity, for internal rotation at
angles and directions of 0°-IR, 30°-IR were respectively 1.33±0,59°, 1.37±0,49°, and for external rotation
at angles and directions of 0°-ER, 30°-ER were respectively 1.39±0,49°, 1.18±0,42° for the non-dominant
side extremity. For neither of the two extremities, the differences between the sense of movement were
statistically significant (p<0.05).
Conclusion: According to the results of the study, shoulder proprioception of dominant and non-dominant
extremities is not different. The goal of proprioception in the rehabilitation of shoulder-related injuries;
regardless of whether the injured extremity is dominant or not, may be determined according to the
shoulder proprioception of the sturdy extremity .

Aim: The aim of this study is to evaluate the versatility of the use of FDMA flaps in soft tissue defects in
the fingers.
Patients and methods: Patients who underwent reconstruction due to soft tissue defect in the upper
extremity between May 2018 and May 2021 were scanned over the file. Among these patients, patients
who had a finger defect and were reconstructed with the first dorsal metacarpal artery flap were included
in the study .
Results: 12 patients were included in the study. The etiology of the defect was trauma in all patients.
Tunneling technique was used in 5 patients for flap adaptation. No patient experienced total flap or graft
loss. Age, gender, comorbidity, defect localization, defect size and operation time were examined in terms
of complications. No statistically significant difference was detected. Smokers and non-smokers were
examined, no statistically significant difference was found. The use of tunnel for flap adaptation did not
make a statistically significant dif ference in terms of complications.
Conclusion: First dorsal metacarpal artery flap is a very reliable option for defects in the 1st and 3rd
fingers. If the tunnel technique is used, it should be ensured that the tunnel width is suf ficient.

Aim: Studies of paediatric acute pancreatitis have remained in the shadow of adult literature for many
years, and have only increased following the recent acceptance of the severity classification. There is now
a need to determine inflammatory biomarkers which will be able to rapidly predict in the early stage which
patients will develop severe disease. This study's purpose was to research the efficacy as early predictors
and determine cutoff values for inflammatory biomarkers including the systemic immune-inflammation
index (SII), and the neutrophil-lymphocyte ratio (NLR).
Patients and Methods: A retrospective evaluation was made of the clinical characteristics, laboratory
test results, and imaging findings of 53 children diagnosed with acute pancreatitis between 2019-2022.
The study population were separated into groups as ‘mild’ and ‘moderately severe-severe’ according
to severity. The groups were compared in respect of inflammatory markers. Factors predicting disease
severity were evaluated with ROC curve analysis. For the significant cutoff values, positive predictive
value (PPV), negative predictive value (NPV), sensitivity and s pecificity were calculated.
Results: The NLR, and SII values were found to be statistically significantly higher in the “moderately
severe-severe” group than in th “mild” group (p<0.001 for all). The cutoff values of NLR≥3.33 (AUC:0.894,
95% CI:0.81-0.979, PPV 89.7%, NPV 83.3%), and SII≥1225.57 (AUC:0.912, 95% CI:0.831-0.992, PPV
90.0%, NPV 87.0%) were determined to be able to predict disease severity with high sensitivity and
specificity.
Conclusion: The NLR, and SII are inflammatory biomarkers that can make an early prediction of a poor
outcome in paediatric acute pancreatitis. To the best of our knowledge, this is the first study to have
evaluated the prognostic importance of these biomarkers, in pae diatric acute pancreatitis.

Aim: This study evaluated the antibacterial effect of gaseous ozone on multi-drug resistant (MDR)
pathogens with regard to time dependency. Controlling infections with MDR bacteria became a big
challenge for health care professionals. Therefore, the major corcern should be altered to alternative
therapies.
Materials and Methods: The study was performed in Necmettin Erbakan University Meram Medical
Faculty Hospital, Department of Medical Microbiology Laboratory between 21 March to 15 April 2021. Ten
MDR bacteria were evaluated in vitro using in the Petri dishes at seven bacterial concentrations (102-
108 bacteria/dish). The ozone showed its efficacy on these MDR bacteria under the following conditions
applied: 40 μg/ml at 10, 20 and 40 minutes and control (no gas was used). After 24 hours incubation of
plates, the average colony counts for each exposure time of ozone were figured out and transformed to
Log10.
Results: Taking acccount the mean bacterial reduction (log10), the bactericidal effect of ozone was
determined on only methicillin-resistant Staphylococcus aureus, VIM-1 producing Klebsiella pneumoniae
and Carbapenem resistant-Acinetobacter baumannii in 10 minutes exposure. The optimum effect was
generally observed within 20 minutes on tested isolates. However, the MDR-Pseudomonas aeruginosa
showed a relatively lower response to ozone. All bacteria was inactivated over the level at 99% at the end
of the 40 min exposure to ozone.
Conclusions: The gaseous ozone showed satisfactory bactericidal activity on MDR pathogens and its
effect depens on exposure time and type of bacteria. Taken into account, the need for new approaches
for the control of microbial infections in the pandemic world, the optimization of ozone therapy should be
undertaken high priority and more in vivo studies are needed to support in depth understanding of the
ozone ef fect on the inactivation of MDR bacteria.

Aim: Convalescent plasma (CP) therapy has been used for treatment, although it has not been Corona
Virus 2019 Disease (COVID-19) specific antiviral agent so far. However, the effectiveness of CP treatment
on prognosis and mortality is still a matter of debate. In this study, we aimed to share our experiences
about the ef fectiveness of CP treatment in COVID-19.
Materials and Methods: The study was conducted in 126 patients diagnosed with COVID-19 who received
CP treatment in addition to standard treatment between May 2020 and February 2021. 126 patients were
divided into two groups as those who underwent SP within the first five days (Group A) and after five days
(Group B). The patients in these two groups were evaluated in terms of laboratory parameters, clinical
and mortality.
Results: A total of 126 patients were identified (86 patients in Group A and 40 patients in Group B). 119
(94.4%) patients were discharged with recovery, 7 (5.5%) patients died. The mean days of hospitalization
were found to be 11.4±0.7 in Group A and 18.4±1.7 in Group B (p<0.001). Treatment-related lymphocyte,
PLT, fibrinogen and CRP main effect of change was significant (p<0.001). However, the results were
marginally significant when the two groups were compared in terms of D-dimer. When the simple effect is
evaluated; Group A as not significant, while group B was significant. Starting CP treatment 5 days before
or 5 days later did not change the laboratory parameters. However, D-dimer was marginally significant
(p=0.058).
Conclusion: In our study, it was shown that early initiation of CP treatment reduced the hospitalization,
but had no ef fect on mortality and laboratory parameters.

Aim: The aim of this study was to map the skin thickness by determining the epidermis, dermis and total skin thickness of six dif ferent regions of the face.

Patients and Methods: Samples containing 9-10 mm of healthy tissue from the facial skin, scalp, forehead, cheek, ear, nose and lip regions of 90 female and 90 male patients aged between 30 and 80 years were retrospectively included in the study, and epidermis and dermis thicknesses examined with a micrometer under a light microscope.

Results: Epidermis thicknesses of 6 facial regions of 90 female participants included in the study were between 65.91±14.44 μm and 120.91±44.74 μm, dermis thicknesses were between 1150±217.43 μm and 1498.33±388.56 μm, and total skin thicknesses were between 1234.83±217.6 μm and 1599.33±492.2 μm. Epidermis thicknesses of 6 facial regions of 90 male participants included in the study were between 79.08±13.88 μm and 122.75±32.5 μm, dermis thicknesses were between 1106.66±389.82 μm and 1942.5±464.06 μm, and total skin thicknesses were between 1756± 503.75 μm and 2022.5±460.24 μm.

Conclusion: In the female patients, the thinnest epidermis was measured on the scalp and the thinnest epidermis in the male patients was measured on the cheek. The thickest epidermis was on the upper lip in the male and female patients. However, the regions with the thinnest and thickest dermis thicknesses differed according to gender. In further studies, a full map of facial skin thickness can be obtained by dividing the face into more subunits using more multicentre, multiethnic materials.

Wound healing is a physiological process consisting of hemostasis, inflammation, proliferation, and
maturation phases. The disruption that occurs at any stage of these intertwined phases is presented to the
clinician as a chronic wound. The stromal vascular fraction, isolated as a part of the aqueous fraction after
enzymatic or mechanical digestion of lipoaspirate, is an important mesenchymal stem cell reserve, as
well as. It is considered a heterogeneous tissue cocktail due to the preadipocytes, endothelial precursors,
immune cells, hematopoietic cells, fibroblasts and pericytes it contains. Because of its proangiogenic,
antiapoptotic, antifibrotic, immunomodulatory, and anti-inflammatory activities, as well as its advantages
in isolation, stromal vascular fraction has lately acquired prominence in current wound therapy. Although
SVF alone is not effective for wound healing, it is a new and effective technology that provides adequate
cell count and viability for proper wound care and wound bed preparation prior to reconstruction and to
minimize surgical failure.