Makale Arama

Trace element selenium is an important part of the oxidative system. It was shown cardiovascular disease in selenium metabolism disorders. However there is no clear data about selenium level in patients with coronary artery disease (CAD). In this study, we investigated the hair and plasma selenium levels in patients who have severe angiographic coronary artery disease. Total 52 patients were included the study. Thirty eight patients who have severe coronary stenosis (≥50%) were included to CAD group. Control group was consisted 18 patients with normal coronary artery. Hair and plasma specimen was taken from all patients to measure selenium levels (mg/dl). Hair selenium was similar in two groups (Control group: 0.6±0.8 vs. CAD group: 0.4±1.1, p=0.2). Plasma selenium levels was higher in CAD group (Control group: 71±8, vs. CAD group: 80±6, p

Multi-Slice Computed Tomography (MSCT) is a recently introduced non-invasive technique used for the diagnosis of coronary artery disease (CAD). Both MSCT and conventional coronary angiography (CAG) may provide direct visualization of the coronary arteries. To determine the diagnostic accuracy of 128-slice MSCT compared with the results of conventional CAG for the diagnosis of significant coronary artery stenosis. Forty-two eligible patients who underwent 128-slice MSCT with the suspicion of CAD and had any coronary lesion within the whole coronary tree were enrolled prospectively. Subsequently, CAG was performed to confirm the severity of coronary lesions. The records acquired by MSCT coronary angiography and conventional CAG were evaluated by 16-segment model of American Heart Association (AHA). Mean age of the patients was 56±12 years, and mean heart rate prior to the examination was 69±4 bpm (min-max: 54-78). Of 672 coronary segments, 669 were interpretable and evaluated in 42 patients. For all the interpretable segments, overall sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and the diagnostic accuracy (DA) of 128-slice MSCT to detect significant stenosis were 91%, 98.5%, 93.8%, 97.8% and 97%, respectively. These values for evaluation of proximal segments were 97.8%, 96.4%, 95.7%, 98.1% and 97.1% and, for distal segments were 87.4%, 98.8%, 92.7%, 97.7% and 97%, respectively. Our results show that, the diagnostic performance of MSCT appear almost equivalent to CAG, current gold standard, with excellent, sensitivity, specificity, positive and negative predictive values. We think that, 128 slice-MSCT will be increasingly utilized in future, decreasing unnecessary coronary angiography procedures.

Myocardial bridge(MB) is common congenital anomaly of coronary arteries. Altough MB is generally asymptomatic, it can manifest as angina pectoris, acute myocard infarction, very rarely fatal cardiac arrhythmias and even sudden death. 44 years old man admitted to our cardiology clinic with typical chest pain and signs of anterior ischemia at electrocardiography, coronary angiography was performed and a myocardial bridge which cause total occlusion at mid-segment of left anterior descending artery detected. In this case report we aimed to discuss mechanism of symptoms, medical and invasive theraphy options and long term follow outcomes in MB.

Patients with isolated single coronary anomaly were retrospectively evaluated for clinical features, angiographic findings and treatment options. Medical records of 27714 patients, who had undergone diagnostic coronary angiography in Türkiye Yüksek İhtisas Hospital between October 2005 and October 2008, were researched and 10 patients with the diagnosis of isolated single coronary artery were recruited into the study. The mean age of patients were 60±13 years (ranging from 33 to 77), 4 of them were men (40%) and 6 were women (60%); mean ages 49±14,5 years (ranging from 33 to 68) and 67±8 years (ranging from 60 to 77), respectively. The patient’s clinical and demographic features on admission, the treatment method used were recorded and the records of coronary angiography were examined again and were classified according to modified Lipton’s classification. Isolated single coronary artery anomaly was diagnosed in 10 patients in the group of a 27714 patients who had undergone coronary angiography. Single coronary artery was originating from right sinus valsalva in 9 patients (90%), and from left sinus valsalva in a patient (10%). Four patients (40%) had severe atherosclerosis and 2 of them had undergone coronary by-pass surgery. The rest of the patients were followed-up under medical treatment. Although isolated single coronary artery anomaly is a rare entity, in hospitals in which coronary angiographic procedures are frequent, its incidence is incidentally more common. In most of the cases clinical outcomes are well and medical treatment and follow-up is enough. In cases which we plan coronary intervention, clinical features, presence of the atherosclerotic disease and the type of coronary anomaly should be watched out.